Engineering the Provitamin A (β-Carotene) Biosynthetic Pathway into (Carotenoid-Free) Rice Endosperm
SciencePublished 14 January 2000
Xudong Ye, Salim Al‐Babili, Andreas Klöti, Jing Zhang, Paola Lucca, Peter Beyer
Citations2,277
SJR quartileQ1
SJR score10.42
SNIP6.62
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TL;DR
Recombinant DNA technology was used to improve the nutritional value of rice, and a combination of transgenes enabled biosynthesis of provitamin A in the endosperm.
Abstract
Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm.
Keywords
Biochemistry, Genetics and Molecular Biology
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