In or out? Regulating nuclear transport
Current Opinion in Cell BiologyPublished 1 April 1999
Jennifer K. Hood, Pamela A. Silver
Citations137
SJR quartileQ1
SJR score2.78
SNIP1.19
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TL;DR
The compartmentalization of proteins within the nucleus or cytoplasm of a eukaryotic cell offers opportunity for regulation of cell cycle progression and signalling pathways and substrate phosphorylation emerged as a common mechanism for controlling this interaction.
Abstract
The compartmentalization of proteins within the nucleus or cytoplasm of a eukaryotic cell offers opportunity for regulation of cell cycle progression and signalling pathways. Nuclear localization of proteins is determined by their ability to interact with specific nuclear import and export factors. In the past year, substrate phosphorylation has emerged as a common mechanism for controlling this interaction.
Keywords
Biochemistry, Genetics and Molecular Biology
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