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2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism

Biochemical PharmacologyPublished 1 January 1988
Martin Grootveld, Barry Halliwell
Citations100
SJR quartileQ1
SJR score1.60
SNIP1.24

TL;DR

2,3-Dihydroxybenzoic acid is present in blood plasma and urine of healthy human volunteers after aspirin ingestion and its identity has been confirmed by mass spectrometry and by electrochemical analysis.

Abstract

2,3-Dihydroxybenzoic acid is present in blood plasma and urine of healthy human volunteers after aspirin ingestion. Its identity has been confirmed by mass spectrometry and by electrochemical analysis. Methods for its identification and measurement are described. The concentration of 2,3-dihydroxybenzoic acid is much lower than that of 2,5-dihydroxybenzoic acid, salicylic acid or salicyluric acid.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology