Decreased Brain GABAA-Benzodiazepine Receptor Binding in Panic Disorder
Archives of General PsychiatryPublished 1 August 1998
Andrea L. Malizia, Vincent J. Cunningham, Caroline Bell, Peter F. Liddle, Terry Jones, David J. Nutt
Citations356
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TL;DR
There is a global reduction in benzodiazepine site binding throughout the brain in patients with panic disorder compared with controls, and results demonstrate that decreased flumazenil binding at this site may underlie panic disorder.
Abstract
These results must be considered preliminary but are congruous with previous clinical psychopharmacologic evidence of involvement of the benzodiazepine-GABA(A) receptor and demonstrate that decreased flumazenil binding at this site may underlie panic disorder.
Keywords
PsychologyNeuroscience
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