Sex behavior after neonatal progesterone, testosterone, estrogen, or antiandrogens

It is asserted that not only must a critical period be considered in evaluating developmental influences on sexual performance but so too must the steroidal environment in terms of type and dosage.

Abstract

The effect on adult sexual behavior of high doses of progesterone and testosterone given to neonatal male rats were tested and compared with the effects of administered estrogen, cyproterone, and cyproterone acetate. Results indicated that high doses of all the test substances affect male sexual performance; the direction of change, however, is dependent upon the parameter measured. It is asserted that not only must a critical period be considered in evaluating developmental influences on sexual performance but so too must the steroidal environment in terms of type and dosage. High dosages used in the study are seen as possible experimental models of the abnormal hormonal milieu associated with certain clinical situations.