Failure of the opiate antagonist naloxone to modify hypnotic analgesia.
Proceedings of the National Academy of SciencesPublished 1 June 1975Open access
A Goldstein, Ernest R. Hilgard
Citations159
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TL;DR
The hypothesis that some features of hypnotic analgesia are mediated through neuronal pathways activating specific opiate receptors in brain are not confirmed and the opiate antagonist naloxone had no effect on hypnotics analgesia in three subjects.
Abstract
Hypnotic analgesia in some respects resembles opiate analgesia. We tested the hypothesis that some features of hypnotic analgesia are mediated through neuronal pathways activating specific opiate receptors in brain. The opiate antagonist naloxone had no effect on hypnotic analgesia in three subjects. Thus, the hypothesis was not confirmed.
Keywords
Neuroscience
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