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Mineralocorticoid receptors in brain, in health and disease: Possibilities for new pharmacotherapy

European Journal of PharmacologyPublished 21 January 2008
Michael Kellner, Klaus Wiedemann
Citations32
SJR quartileQ1
SJR score1.20
SNIP0.98

TL;DR

Recent research findings promise possibilities for new pharmacotherapy via modulation of mineralocorticoid receptor function, which is involved in the regulation of stress hormone secretion and complex behavior, such as emotion, memory, and sleep.

Abstract

Mineralocorticoid receptors in brain are involved in the regulation of stress hormone secretion and complex behavior, such as emotion, memory, and sleep. In man, the role of mineralocorticoid receptors in the pathophysiology of stress-related psychiatric disorders has still not sufficiently been characterized. Nevertheless, recent research findings promise possibilities for new pharmacotherapy via modulation of mineralocorticoid receptor function.

Keywords

MedicineNeuroscience