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Drug Treatment of Parkinson’s Disease

InPharmaPublished 1 September 1984
E.N.H. Jansen
Citations9

Abstract

The symptoms of idiopathic Parkinson’s disease are due mainly to progressive degeneration of the dopaminergic nigro-striatal pathways in the brain. The drugs which can help fall into five categories: dopamine replacement, using dopa with a decarboxylase inhibitor; a dopamine agonist, bromocriptine; 1 selegiline, recently introduced, which inhibits monoamine oxidase B; anticholinergic drugs; and amantadine. 2 This article discusses recent ideas about the management of Parkinson’s disease, particularly about levodopa dosage, bromocriptine and selegiline.

Keywords

ChemistryMedicineNeuroscience