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Influence of maternal age at delivery and birth order on risk of type 1 diabetes in childhood: prospective population based family study

BMJPublished 12 August 2000Open access
P. J Bingley
Citations125
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TL;DR

The fetal environment seems to have a strong influence on risk of type 1 diabetes in the child, and the increase in maternal age at delivery in the United Kingdom over the past two decades could partly account for the rise in incidence of childhood diabetes over this period.

Abstract

A strong association was found between increasing maternal age at delivery and risk of diabetes in the child. Risk was highest in firstborn children and decreased progressively with higher birth order. The fetal environment seems to have a strong influence on risk of type 1 diabetes in the child. The increase in maternal age at delivery in the United Kingdom over the past two decades could partly account for the increase in incidence of childhood diabetes over this period.

Keywords

Medicine