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External validation is necessary in prediction research:

Journal of Clinical EpidemiologyPublished 1 September 2003
Sacha E. Bleeker, Henriëtte A. Moll, Ewout W. Steyerberg, A. Rogier T. Donders, G Derksen‐Lubsen, Diederick E. Grobbee
Citations697
SJR quartileQ1
SJR score3.15
SNIP2.66

TL;DR

For relatively small data sets, internal validation of prediction models by bootstrap techniques may not be sufficient and indicative for the model's performance in future patients.

Abstract

For relatively small data sets, internal validation of prediction models by bootstrap techniques may not be sufficient and indicative for the model's performance in future patients. External validation is essential before implementing prediction models in clinical practice.

Keywords

Medicine