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The role of calcium–calmodulin kinase II in three forms of synaptic plasticity

Current BiologyPublished 1 August 1994
Charles F. Stevens, Susumu Tonegawa, Yanyan Wang
Citations183
SJR quartileQ1
SJR score2.71
SNIP1.83

TL;DR

It is proposed that the activation of this enzyme is a common step in the induction of LTP and STP, and that alpha CaMKII activity is required for the normal production of LTD.

Abstract

It appears likely that alpha CaMKII is involved in the production or global regulation of all three forms of synaptic plasticity. We propose that the activation of this enzyme is a common step in the induction of LTP and STP, and that alpha CaMKII activity is required for the normal production of LTD.

Keywords

MedicineNeuroscience