Partial Purification and Characterization of Natriuretic Factor from Rat Kidney
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TL;DR
A partial purification of natriuretic factor from volume-expanded rat kidney has been achieved by Sephadex gel chromatography and acrylamide gel electrophoresis and inhibits frog skin SCC and Na-K-ATPase from different sources in a dose-dependent manner.
Abstract
A partial purification of natriuretic factor from volume-expanded rat kidney has been achieved by Sephadex gel chromatography and acrylamide gel electrophoresis. This factor inhibits frog skin SCC and Na-K-ATPase from different sources in a dose-dependent manner. Activity is destroyed by incubation with trypsin or fresh kidney homogenate but not chymotrypsin.