Elastic filaments and giant proteins in muscle
Current Opinion in Cell BiologyPublished 1 February 1991
John Trinick
Citations85
SJR quartileQ1
SJR score2.78
SNIP1.19
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TL;DR
Striated muscle is now known to contain a third major class of filaments, additional to the thick and thin filaments.
Abstract
Striated muscle is now known to contain a third major class of filaments, additional to the thick and thin filaments. The presence of such extra filaments has seemed likely for many years, but details of their location, structure, and composition are only now becoming clear. They are composed of massively large proteins and, in contrast to thick and thin filaments, they are elastic.
Keywords
MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology
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Observations suggest that newly synthesized titin molecules are stable proteins that rapidly associate with the cytoskeleton of developing myotubes.
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