Yeast chromosome replication and segregation
Microbiological ReviewsPublished 1 December 1988Open access
Carol S. Newlon
Citations241
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TL;DR
This chapter discusses the construction of Chromosome Structure and its applications in DNA Replication, and the role of DNA sequence homology in this process.
Keywords
Agricultural and Biological SciencesBiochemistry, Genetics and Molecular Biology
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NatureA role for the nuclear envelope in controlling DNA replication within the cell cycle
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CellATP activates dnaA protein in initiating replication of plasmids bearing the origin of the E. coli chromosome
468 Citations1987Kazuhisa Sekimizu, David Bramhill +1 more
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453 Citations1983Andrew W. Murray, Jack W. Szostak
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NatureNeed for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA
436 Citations1987Steven J. Brill, Stephen DiNardo +2 more
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250 Citations1988Bruno Amati, Susan M. Gasser
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232 Citations1987Rhona H. Borts, James E. Haber
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231 Citations1984Lex H.T. Van der Ploeg, Alvin Y.C. Liu +1 more
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223 Citations1980Clarence S.M. Chan, Bik‐Kwoon Tye
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Proceedings of the National Academy of SciencesRAD3 protein of Saccharomyces cerevisiae is a DNA helicase.
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217 Citations1986Fredric C. Volkert, James R. Broach
It is shown that the site-specific recombination system of 2 mu circle enables the plasmid to increase its mean intracellular copy number in yeast cells growing under nonselective conditions.
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217 Citations1986M Snyder, Andrew R. Buchman +1 more
The existence of bent DNA is shown at a yeast autonomously replicating sequence (ARS1), a putative replication origin, and may be involved in transcription termination or the prevention of nucleosome assembly in this region.
CellReplication of each copy of the yeast 2 micron DNA plasmid occurs during the S phase
212 Citations1979Virginia A. Zakian, Bonita J. Brewer +1 more
The results show that replication of 2 micron DNA occurs by a semiconservative mechanism where each of the plasmid molecules replicates once each cell cycle, and indicate that a mechanism exists which insures that the origin of replication of each 2 microns DNA molecule is activated each S phase.
Molecular and Cellular BiologyGenetic manipulation of centromere function.
209 Citations1987Alison Hill, Kerry Bloom
Molecular and Cellular BiologyDeletion mutations affecting autonomously replicating sequence ARS1 of Saccharomyces cerevisiae.
206 Citations1984S Celniker, Kevin Sweder +3 more
Rather than identifying a distinct and continuous segment that mediates the ARS+ phenotype, this work finds three different functional domains within ARS1, which cannot mediate high-frequency transformation, or replicate by itself, and is required for efficient, stable replication of plasmids containing domain A.
Molecular and Cellular BiologySimian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication.
205 Citations1985Jian Jian Li, Thomas J. Kelly
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203 Citations1987Stephen J. Elledge, Ronald W. Davis
The expression of these genes defines a new mode of regulation for enzymes involved in DNA biosynthesis and sharpens the picture of the events leading to DNA repair in eucaryotic cells.
CellA yeast replication origin consists of multiple copies of a small conserved sequence
197 Citations1988Timothy Palzkill, Carol S. Newlon
It is found that two copies of the core consensus are sufficient for ARS activity and that an artificial ARS as efficient as a natural chromosomal ARS can be constructed from multiple core consensus elements in a specific orientation.
Annual Review of Cell BiologyChromosome Segregation in Mitosis and Meiosis
196 Citations1985Andrew W. Murray, Jack W. Szostak
A MODEL for CHROMOSOME BEHAVIOR DURING MITOSIS and MEIOSIS is presented to help researchers understand the dynamics of the cell cycle.
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192 Citations1985Lianna M. Johnson
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191 Citations1985C Thrash, Alan T. Bankier +2 more
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191 Citations1984A. B. Futcher, B. S. Cox
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178 Citations1984Tadaatsu Goto, James C. Wang
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173 Citations1988Joel A. Huberman, Jiguang Zhu +2 more
Two dimensional gel electrophoretic techniques were used to locate all functional DNA replication origins in a 22.5 kb stretch of yeast chromosome III, and only one origin was detected.
The EMBO JournalRoles of two DNA‐binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer.
173 Citations1988William J. Kimmerly, Andrew R. Buchman +2 more
The results suggest that the SIR proteins influence the properties of the HMR E silencer through interactions with other DNA‐binding proteins.
ScienceUnwinding of Duplex DNA from the SV40 Origin of Replication by T Antigen
172 Citations1987Mark S. Dodson, Frank B. Dean +3 more
Observations with the SV40 system indicate that localized initiation of duplex DNA replication may be similar for prokaryotes and eukaryotes.
Cold Spring Harbor Symposia on Quantitative BiologyProperties of Yeast Transformation
171 Citations1979James Hicks, A. Hinnen +1 more
Several additional aspects of yeast transformation are described along with results showing that integrated bacterial plasmid sequences can be retrieved from the yeast genome and reintroduced into bacteria as replicant plasmids.
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