Asymmetric Two‐Center Catalysis—Learning from Nature

Abstract

In spite of relatively few examples, two-center catalysis is proving to be a clever and effective means of performing diverse reactions with both high regio- and enantioselectivity. A simple scheme allows classification of the efficient M1–M2–binol complexes 1 as well as the enzymes urease and carbon monoxide dehydrogenase. M1 = La, Al,…; M2 = Li, Na, K,….