Th1-Th2: Reliable paradigm or dangerous dogma?
Immunology TodayPublished 1 August 1997
Judith E. Allen, Rick M. Maizels
Citations304
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TL;DR
The identification of crossregulating T helper (Th) cells has revolutionized current understanding of the immune response to infection, but Judith Allen and Rick Maizels argue that the paradigm can be dangerously oversimplified.
Abstract
The identification of crossregulating T helper (Th) cells has revolutionized current understanding of the immune response to infection. While paying tribute to this revolution, Judith Allen and Rick Maizels argue that the paradigm can be dangerously oversimplified and that the interaction between host and pathogen cannot always be addressed in the context of Th1 and Th2 cells.
Keywords
Immunology and Microbiology
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