Six red flags for suspect work
NaturePublished 21 May 2013Open access
C. Glenn Begley
Citations234
SJR quartileQ1
SJR score18.29
SNIP10.16
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
Abstract
C. Glenn Begley explains how to recognize the preclinical papers in which the data won't stand up.
NatureRaise standards for preclinical cancer research
2,930 Citations2012C. Glenn Begley, Lee M. Ellis
C. Glenn Begley and Lee M. Ellis propose how methods, publications and incentives must change if patients are to benefit.
Nature Reviews Drug DiscoveryBelieve it or not: how much can we rely on published data on potential drug targets?
1,924 Citations2011Florian Prinz, Thomas Schlange +1 more
It is indicated that the limitations of the predictivity of disease models and also that the validity of the targets being investigated is frequently questionable, which is a crucial issue to address if success rates in clinical trials are to be improved.
NatureKnow when your numbers are significant
129 Citations2012David L. Vaux
Experimental biologists, their reviewers and their publishers must grasp basic statistics, urges David L. Vaux, or sloppy science will continue to grow.