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Cerebrospinal fluid levels of oxytocin in Prader–Willi syndrome: a preliminary report

Biological PsychiatryPublished 1 December 1998Open access
Andrés Martin, Matthew W. State, George M. Anderson, Walter M Kaye, Jeanne M. Hanchett, Claire McConaha
Citations87
SJR quartileQ1
SJR score4.68
SNIP2.24
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TL;DR

CSF oxytocin was elevated in Prader-Willi syndrome as compared to normal control subjects, and AVP was not significantly different between the groups as a whole, providing further evidence for hypothalamic and Oxytocinergic dysfunction in PWS.

Abstract

These data provide further evidence for hypothalamic and oxytocinergic dysfunction in PWS. The associations between oxytocin, appetite regulation, and obsessive compulsive symptomatology in PWS warrant further investigation.

Keywords

NeuroscienceBiochemistry, Genetics and Molecular Biology