Efficacy of a quadrivalent prophylactic human papillomavirus (types 6, 11, 16, and 18) L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: a combined analysis of three randomised clinical trials
The LancetPublished 1 May 2007
Elmar A. Joura, Sepp Leodolter, Mauricio Hernández‐Ávila, Cosette M. Wheeler, Gonzalo Pérez, Laura A. Koutsky
Citations576
SJR quartileQ1
SJR score12.11
SNIP22.72
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TL;DR
Prophylactic administration of quadrivalent HPV vaccine was effective in preventing high-grade vulval and vaginal lesions associated with HPV16 or HPV18 infection in women who were naive to these types before vaccination.
Abstract
Prophylactic administration of quadrivalent HPV vaccine was effective in preventing high-grade vulval and vaginal lesions associated with HPV16 or HPV18 infection in women who were naive to these types before vaccination. With time, such vaccination could result in reduced rates of HPV-related vulval and vaginal cancers.
Keywords
Medicine
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