Performance of the Aptima HIV-1 RNA Qualitative Assay with 16- and 32-Member Specimen Pools
Journal of Clinical MicrobiologyPublished 1 July 2010Open access
Steven F. Ethridge, Clyde E. Hart, Debra L. Hanson, Monica M. Parker, Timothy J. Sullivan, Berry Bennett
Citations11
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TL;DR
The Aptima HIV-1 RNA qualitative assay tested with a WHO-approved HIV type 1 RNA standard in 16- and 32-member pools detected 100% of the pools, thus exceeding the FDA-required lower limit of detection.
Abstract
The Aptima HIV-1 RNA qualitative assay tested with a WHO-approved HIV type 1 RNA standard in 16- and 32-member pools detected 100% of the pools (1,070 and 2,130 HIV-1 RNA copies/ml/pool, respectively), thus exceeding the FDA-required lower limit of detection. The Aptima test can be used to screen for acute-phase HIV infection.
Keywords
Immunology and MicrobiologyMedicine
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