The periodic health examination. Canadian Task Force on the Periodic Health Examination.
PubMedPublished 3 November 1979Open access
Citations284
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MedicineHealth Professions
Clinical EndocrinologyTHE SPECTRUM OF THYROID DISEASE IN A COMMUNITY: THE WHICKHAM SURVEY
2,690 Citations1977W. M. G. Tunbridge, D C Evered +8 more
TSH levels above 6 mu/1 were shown to reflect a significant lowering of circulating thyroxine levels and showed a strong association with thyroid antibodies in both sexes, independent of age.
New England Journal of MedicineHigh Association of an HL-A Antigen, W27, with Ankylosing Spondylitis
1,371 Citations1973Lee H. Schlosstein, Paul I. Terasaki +2 more
The frequencies of 24 HL-A antigens were examined in patients with ankylosing spondylitis, 119 with rheumatoid arthritis, and 66 with gout, finding no significant deviation from control frequen...
New England Journal of MedicineThe Fetal Alcohol Syndrome
1,360 Citations1978Sterling K. Clarren, David W. Smith
JNCI Journal of the National Cancer InstituteEtiology of Human Breast Cancer: A Review2
774 Citations1973Brian MacMahon, Philip Cole +1 more
The hypothesis that breast cancer risk is related to estrogen metabolism during the first few years after menarche is the hypothesis most compatible with all the major epidemiological features of the disease and is virtually the only acceptable explanation.
BMJMortality in Relation to Smoking: Ten Years' Observations of British Doctors
680 Citations1964Richard Doll, A. B. Hill
Evidence supports the claim that cigarette smoking is one of the causes of coronary thrombosis under age 75 and continued smoking may prevent or delay the healing of a chronic gastric ulcer and thereby it may increase the mortality rate.
New England Journal of MedicineDissolution of Cholesterol Gallstones by Chenodeoxycholic Acid
657 Citations1972R. G. Danzinger, Alan F. Hofmann +2 more
Chenodeoxycholic acid may offer medical treatment for cholesterol cholelithiasis in man and the ratio of bile acids and lecithin to cholesterol in bile increased in all patients.
New England Journal of MedicineCongenital Toxoplasmosis
646 Citations1974G Desmonts, J Couvreur
Treatment with spiramycin during pregnancy reduced the overall frequency of the fetal infections but not of overt disease, and Mothers with antibodies before they became pregnant had no infected infants.
CancerThe veterans administration cooperative urological research group's studies of cancer of the prostate
598 Citations1973David P. Byar
The overall recommendation at present is that patients with prostatic cancer should not be treated until their symptoms require relief, and at that time it is recommended starting treatment with 1.0 mg DES daily.
Journal of Chronic DiseasesThe epidemiology of gallbladder disease: Observations in the Framingham study
525 Citations1966Gary Friedman, William B. Kannel +1 more
It would appear that more attention should be devoted to the anatomy and pathological physiology of the biliary tract in seeking a better understanding of the pathogenesis of gallbladder disease.
New England Journal of MedicineIncreased Absenteeism from Work after Detection and Labeling of Hypertensive Patients
519 Citations1978R. Brian Haynes, David L. Sackett +3 more
It is found that absenteeism rose 80 per cent after screening and referral among patients unaware of their hypertension before screening, which greatly exceeded the 9 per cent rise in absenteeism in the general employee population during this period.
The Journal of Nervous and Mental DiseaseCONDITIONS PREDISPOSING TO SUICIDE
507 Citations1977Charles P. Miles
By reviewing causes of death among cohorts of various major disease entities or conditions, one may infer that a large majority of suicides are associated with a relatively small number of conditions.
Journal of Studies on AlcoholAlcoholism: a controlled trial of "treatment" and "advice".
493 Citations1977Griffith Edwards, Jim Orford +7 more
Two groups of alcoholics received either one counseling session or several months of in- and outpatient treatment, with no significant differences in outcome between the two groups one year later.
CirculationCoronary Artery Disease in 116 Kindred with Familial Type II Hyperlipoproteinemia
481 Citations1974Neil J. Stone, Robert I. Levy +2 more
This study, the largest of its kind, permitted more precise and extensive determination of the CAD risk accompanying severe hyperbetalipoproteinemia than has heretofore been possible.
JAMAPeriodic Breast Cancer Screening in Reducing Mortality From Breast Cancer
475 Citations1971Sam Shapiro
The 3 1/2-year case fatality rates among women with histologically confirmed breast cancers reinforce the impression that screening leads to lowered mortality, and more time is needed to establish whether the effect of the screening program is short-term or long-term.
New England Journal of MedicineCourse and Prognosis of Chronic Obstructive Lung Disease
439 Citations1969Benjamin Burrows, Richard H. Earle
Most features of the disease showed a systematic tendency to worsen, but yearly changes were relatively small, often becoming evident only with long-term observation, compatible with the concept that chronic obstructive lung disease is a slowly progressive disorder that begins many years before the onset of clinical symptoms.
PEDIATRICSTrends in Fatness and the Origins of Obesity
424 Citations1976Stanley M. Garn, D. Cecil Clark +9 more
The TSNS has provided nine-decade triceps or subscapular fatfold data on more than 40,000 individuals, showing both an economic-related fatness increase in the male at all ages and an economic "reversal" of fatness in the female at adolescence and beyond.
New England Journal of MedicineAdverse Effects on Offspring of Maternal Alcohol Abuse during Pregnancy
422 Citations1977Eileen M. Ouellette, Henry L. Rosett +2 more
Infants born to heavy drinkers had twice the risk of abnormality of those born to abstinent or moderate drinkers, and microcephaly and multiple congenital anomalies were much more frequent in this group.
Archives of Disease in ChildhoodEffect of Human Growth Hormone Treatment for 1 to 7 Years on Growth of 100 Children, with Growth Hormone Deficiency, Low Birthweight, Inherited Smallness, Turner's Syndrome, and Other Complaints
390 Citations1971J. M. Tanner, R. H. Whitehouse +2 more
There was a highly significant relation between blood GH peak level and pretreatment height velocity in the HS patients, and partial HS patients are accelerated by HGH and should be treated; but their average acceleration is below that of total HS patients.
American Journal of Obstetrics and GynecologyPrenatal and intrapartum high-risk screening
370 Citations1973Calvin J. Hobel, Marcia A. Hyvarinen +2 more
A high-risk pregnancy screening system based on a prospective analysis of prenatal, intrapartum, and neonatal factors in 738 pregnancies can predict perinatal morbidity and mortality.
The Journal of PediatricsPreliminary report on a mass screening program for neonatal hypothyroidism
361 Citations1975Jean H. Dussault, Pierre A. Coulombe +4 more
The frequency of congenital hypothyroidism is about one in 7,000 births and the immunoassay is effective in detecting thyroid hormone abnormalities with an acceptable percentage of false positive measurements; no false negative results have occurred.
New England Journal of MedicineContinuous Subcutaneous Administration of Deferoxamine in Patients with Iron Overload
333 Citations1977Richard D. Propper, Barry Cooper +6 more
Constant subcutaneous deferoxamine administration may prove to be an effective and practical means of eliminating large quantities of iron in siderosis.
The Journal of PediatricsImproved prognosis in congenital bypothyroidism treated before age three months
326 Citations1972Alan H. Klein, Stephanie Meltzer +1 more
The relationship between age at beginning therapy and subsequent intelligence quotient was studied in patients with congenital hypothyroidism, and patients treated before three months of age had a significantly higher average I.Q. than those treated after three months.
American Journal of EpidemiologyPERINATAL EVENTS ASSOCIATED WITH MATERNAL SMOKING DURING PREGNANCY1
302 Citations1976MARY B. MEYER, Bruce S. Jonas +1 more
Maternal smoking had the strongest effect on birthweight in the 8 factor regression, and birth less than 2500 gm increased directly with smoking level from 20% to 340% in 37 data subgroups.
New England Journal of MedicineEfficacy and Specificity of Chenodeoxycholic Acid Therapy for Dissolving Gallstones
292 Citations1973Johnson L. Thistle, Alan F. Hofmann
In a controlled trial, 53 patients with asymptomatic radiolucent gallstones in functioning gallbladders were treated with chenodeoxycholic acid, cholic acid or placebo and at six months, 11 of them had gallstones removed.
Archives of Pediatrics and Adolescent MedicineLow Birth Weight and the Battered Child Syndrome
267 Citations1971Michael Klein
Fifty-one cases of battered child syndrome seen over a period of nine years at the Montreal Children's Hospital were reviewed to explore the possibility that low birth weight predisposes to this condition.
The LancetGALLSTONE DISSOLUTION IN MAN USING CHENODEOXYCHOLIC ACID
259 Citations1972G. D. Bell, Brian Whitney +1 more
Chenodeoxycholic acid treatment significantly improved cholesterol solubility in bile as shown by an increase in the cholesterol Solubilising capacity of bile (the bile-salt + phospholipid/cholesterol ratio) and by a reduction in the molar ratio of cholesterol in biles.
New England Journal of MedicineToxoplasmosis in the Adult — An Overview
247 Citations1978James A. Krick, Jack S. Remington
Toxoplasma gondii is clinically important in the adult for three major reasons: it may cause lymphadenopathy; as an opportunist, it maycause a lethal infection in the immunologically compromised host; and it is responsible for at least 3000 congenitally infected infants in the United States yearly, thus making correct interpretation of serologic tests in the woman who is pregnant (or thinking of becoming so) an urgent matter.
PubMedPrenatal diagnosis of genetic disease in Canada: report of a collaborative study.
244 Citations1976Nancy E. Simpson, Louis Dallaire +5 more
2nd-trimester amniocentesis at about 16 weeks' gestation is a safe, accurate and reliable procedure for the diagnosis of certain classes of genetic disease when it is monitored by ultrasound, performed by a trained obstetrician and carried out in a major health sciences centre.
New England Journal of MedicineDetection of Prostatic Cancer by Solid-Phase Radioimmunoassay of Serum Prostatic Acid Phosphatase
244 Citations1977Andras Foti, J. Fenimore Cooper +2 more
The radioimmunoassay test was positive in two patients with benign prostatic hyperplasia, in one patient after total prostatectomy, in nine with other cancers and in one of the group with gastrointestinal disorders, and distinguished over half the cases of intracapsular prostatic cancer.
The LancetNEONATAL COAGULATION DEFECT DUE TO ANTICONVULSANT DRUG TREATMENT IN PREGNANCY
217 Citations1970K. R. Mountain, J. Hirsh +1 more
It is suggested that anticonvulsant drug therapy during pregnancy, especially treatment with barbiturates, frequently causes a coagulation defect which may result in bleeding during the early neonatal period and the prophylactic use of vitamin K 1 is especially important in this situation.
New England Journal of MedicineDiet-Heart: End of an Era
210 Citations1977George V. Mann
A generation of research on the diet-heart question has ended in disarray, and the official line since 1950 for management of the epidemic of coronary heart disease has been a dietary treatment.
CancerOccult blood testing for detection of asymptomatic colon cancer
204 Citations1971David H. Greegor
To facilitate multiple stool testing, the authors made use of commercially available guaiac‐impregnated slides and believe that every adult should have this screening test annually.
DrugsCarbenoxolone
167 Citations1976Ruth Pinder, Rex N. Brogden +4 more
Carbenoxolone is of greatest benefit in accelerating the healing of gastric ulcers in patients for whom hospitalisation is not possible or desirable, but it should only be used in the ambulatory patient when careful and regular observation of serum electrolytes, blood pressure and weight is possible and when it is known that the patient will attend regular follow-up.
New England Journal of MedicinePrenatal Diagnosis of Hemoglobinopathies
164 Citations1976Blanche P. Alter, C. B. Modell +6 more
Although prenatal diagnosis of hemoglobinopathies is feasible, the present frequency of fetal loss and diagnostic error indicates need for improvement.
BMJ134 Battered Children: A Medical and Psychological Study
159 Citations1974Selwyn M. Smith, Ruth Hanson
A controlled investigation of 134 battered children showed that nearly half had serious injuries and 21 died, and the risk of battering diminishes after a child's second birthday.
University of Pennsylvania Press eBooks12. The Social Consequences of Teenage Parenthood
159 Citations1981Frank F. Furstenberg
The adolescent mothers consistently experienced great difficulty in realizing their life plans, when compared with their classmates who did not become pregnant premaritally in their early teens.
American journal of diseases of childrenHemorrhagic Disease of the Newborn
151 Citations1967James M. Sutherland
The present studies were undertaken to define the frequency of hemorrhagic disease of the newborn in the medically indigent population of Cincinnati and to redefine an effective prophylactic.
New England Journal of MedicineLithogenic Bile among Young Indian Women
146 Citations1971Johnson L. Thistle, Leslie J. Schoenfield
It is suggested that lithogenic bile precedes gallstone formation in Chippewa women and that administration of chenodeoxycholic acid decreases this lithogenic potential.
The LancetIS THERE A SCIENTIFIC BASIS FOR SIX-MONTHLY DENTAL EXAMINATIONS?
144 Citations1977Aubrey Sheiham
Routine 6-monthly screening to detect oral malignancies is unreasonable, because there are no data on the rates of progression of diseases of the primary dentition and there is no evidence that an interval of more than 6 months would affect the prognosis for orthodontic treatment.
MedicineDEMOGRAPHIC AND PROGNOSTIC CHARACTERISTICS OF BACTERIURIA IN PREGNANCY
143 Citations1967Wendy E. Savage, Samir N. Hajj +1 more
PEDIATRICSLOW BIRTH WEIGHT AND PRENATAL NUTRITION: AN INTERPRETATIVE REVIEW
143 Citations1970Lawrence Bergner, Mervyn Susser
Three conclusions are germane to the prevention of low birth weight: first, the fetal growth that leads to important variation in birthweight occurs in the last trimester; second, birth weight is influenced by factors in the wider environment as well as in the maternal environment; and third,Birth weight is influences by factors having their origin and effect during gestation.
The LancetCAUSES OF SHORT STATURE
139 Citations1974Karen Lacey, J M Parkin
It is concluded that unless there are symptoms or clear signs of disease, investigation of a short child to exclude an organic explanation is indicated only if the height is further than 3 S.D.S below the mean or the growth-rate is slow.
American Journal of Public HealthPrevention of childhood household injuries: a controlled clinical trial.
139 Citations1977Robert A. Dershewitz, John Williamson
Active health education, as used and evaluated in this study, appears to have limited effectiveness when applied to home safety, and approaches such as "passive" measures may offer greater potential for household injury reduction.
American Journal of Obstetrics and GynecologyFetal syphilis in the first trimester
134 Citations1976Carol A. Harter, Kurt Benirschke
The literature supporting the Langhans layer/five months' placental barrier theory is reviewed and discussed in view of these two first-trimester cases of fetal syphilis.
Journal of Epidemiology & Community HealthEpidemiology and family characteristics of severely-abused children.
134 Citations1975J. A. Baldwin, Jack Oliver
The families of the retrospective series of abused children were studied in detail and identifying characteristics of large family size, youthfulness, low social-class, instability, and gross psychiatric, medical, and social pathology described.
PubMedStudies in the epidemiology of prostatic cancer: expanded sampling.
131 Citations1977Rotkin Id
The data suggest that early differences are hormonally conditioned, support a provisional endogenous rationale for initiation of prostatic cancer, and oppose a hypothesis favoring transmissible oncogenic agents.
New England Journal of MedicineCarrier Detection in Duchenne Muscular Dystrophy
124 Citations1976Allen D. Roses, M. J. Roses +3 more
The results suggest that cases of Duchenne muscular dystrophy previously considered to be new mutations are much less common than estimated.
Social Science & Medicine (1967)A measure of family functioning and its application
120 Citations1973I B Pless, Betty Satterwhite
A measure of family functioning, intended to assess the strength of relationships and life style taken as a whole, is described, and the content, reliability and validity are described.
American Journal of Clinical NutritionCardiorespiratory, hematological and physical performance responses of anemic subjects to iron treatment
118 Citations1975GW Gardner, VR Edgerton +2 more
The results clearly support the concept that performance requiring high oxygen delivery is significantly affected by hemoglobin levels, and no difference in oxygen consumption was found between theIron treatment and placebo group although 15% more O2 was delivered per pulse in the iron treatment group.
Archives of OphthalmologyUntreated Ocular Hypertension
116 Citations1977Yoshiaki Kitazawa
Both the sensitivity and the specificity of each clinical finding in the individuals who later developed visual field defects were determined, and none of the clinical findings was found to be a good predictive indicator.
New England Journal of MedicineRecommendations for a National Policy on Poliomyelitis Vaccination
109 Citations1977Elena Nightingale
The relative merits of live and killed virus vaccines as immunizing agents were reviewed within the context of the 60 to 70 per cent level of poliomyelitis vaccination now reached in the United States.
The Journal of PediatricsRelation of breast versus bottle feeding to hospitalization for gastroenteritis in a middle-class U.S. population
108 Citations1978Spencer A. Larsen, Daryl R. Homer
It is found that breast feeding plays a major role in protection against intestinal infections and the lower than predicted incidence of acute gastroenteritis in the breast fed infants was statistically significant.
BJOG An International Journal of Obstetrics & GynaecologyINTRAVENOUS INFUSION OF SALBUTAMOL IN THE MANAGEMENT OF PREMATURE LABOUR
108 Citations1973G. C. Liggins, G. S. Vaughan
It is concluded that salbutamol is a safe, well tolerated and effective uterine relaxant.
The Journal of Infectious DiseasesGastroenteritis in Children: A Two-Year Review in Manitoba. I. Etiology
103 Citations1977Marc Gurwith, T. Walley Williams
Screening for enterotoxigenic or enteroinvasive organisms was not productive of a significant number of pathogens, and, although screening for rotavirus did improve the number of etiologic diagnoses, the etiology of the majority of cases of diarrhea remained unknown.
American Journal of Obstetrics and GynecologySurgical closure of the incompetent cervix during pregnancy
101 Citations1958Robert H. Barter, James A. Dusbabek +2 more
If the patient has a history of repeated middle-trimester pregnancy losses the next most convincing means of proving that the cervix is incompetent is to examine the patient at weekly intervals during gestation, as a cause of habitual abortion in the middle trimester of pregnancy.
Pediatric Clinics of North AmericaCellular Growth in Intrauterine Malnutrition
99 Citations1970Myron Winick
The LancetEVALUATION OF THREE THYROID-FUNCTION SCREENING TESTS FOR DETECTING NEONATAL HYPOTHYROIDISM
96 Citations1976P. G. Walfish
To avoid the impracticably high recallrate and false-positive incidence resulting from an initial T4 screening test, and to reduce the estimated follow-up recall to less than 0-2% of the screened infant population, it is recommended that infants with low T4 be selected for a supplementary T.S.H. screening test.
Journal of HygieneStool viruses in babies in Glasgow: 1. Hospital admissions with diarrhoea
93 Citations1977C.R. Madeley, B. Cosgrove +2 more
Examination of several stools from the same patient showed that in this age group the viral flora of the gut changes rapidly and that the viruses seen by electron microscopy were only rarely grown in cell culture and vice versa.
New England Journal of MedicineImmunization of Adults against Diphtheria and Tetanus
89 Citations1954Johannes Ipsen
The Institute of Laboratories of the Massachusetts Department of Public Health has issued for the last three years twice as many doses of this preparation as the number of annual births in Massachusetts.
PubMedMortality factors in diabetes. A 20 year mortality study.
86 Citations1975G Goodkin
The life expectancy of well controlled diabetics has been considered to be approximately that of the normal individual, but a 20 year prospective study of the mortality ofDiabetics who applied for life insurance to the Equitable Life Assurance Society did not confirm this.
CancerThe present status of cea in diagnosis, prognosis, and evaluation of therapy
83 Citations2006Norman Zamcheck
Despite nonspecificity for the diagnosis of colon cancer, the assays for CEA widely studied to date may be useful in the management of patients with colorectal cancer by aiding detection of colonic cancer and especially of widespread metastases to the liver.
New England Journal of MedicineLong-Term (10 to 14 Years) Follow-up of Bacteriuria of Pregnancy
79 Citations1971Stephen H. Zinner, Edward H. Kass
New England Journal of MedicineScreening for Thalassemia Trait by Electronic Measurement of Mean Corpuscular Volume
77 Citations1973Howard A. Pearson, Richard T. O’Brien +1 more
A large number of patients with Mediterranean ethnic groups have at least one known hereditary blood condition and the results indicate that screening for these conditions is a viable option for clinical and genetic screening.
The British Journal of PsychiatryAntenatal Identification of Women Liable to Have Problems in Managing Their Infants
77 Citations1973Eva A. Frommer, Gillian O'Shea
The investigation which is reported here was designed as a pilot project for a possible later research programme into the prevention of emotional disturbance in mothers and young children.
HeartVentricular septal defect: Incidence, morbidity, and mortality in various age groups
77 Citations1971John D. Keith, Vera Rose +2 more
The true incidence of isolated ventricular septal defect and its subdivisions is difficult to estimate accurately, since the data available in the past have been obtained in a variety of incomplete ways.
BMJEvaluation of Early Diagnostic Services for the Elderly
75 Citations1970Claire Lowther, Rhona MacLeod +1 more
It is concluded that the offer of a routine examination to high risk groups is of benefit to old people and a form of medical practice which should be widely adopted.
JAMAAntacids vs Placebos in Peptic Ulcer Therapy
75 Citations1973Daniel Hollander
In duodenal ulceration, a trend in favor of antacid therapy was found with respect to promotion of healing and relief of peptic discomfort, however, this trend was not statistically significant.
Annual Review of MedicinePertussis in the Adult
74 Citations1977Calvin C. Linnemann, J Nasenbeny
It is believed that pertussis in adults is often unrecognized, and this is accountable in many cases for the spread of the disease.
New England Journal of MedicineTreatment of Gallstones with Chenodeoxycholic Acid and Phenobarbital
73 Citations1975M.J. Coyne, George Bonorris +4 more
American Journal of Public Health and the Nations HealthAn effective weight control program in a public school system.
73 Citations1970Carl C. Seltzer, Jean Mayer
In this judgment, the opportunity for greatest success in the control of obesity lies in tackling the problem in the preadult stage, in obese children and adolescents, when the habits of diet and physical activity are more tractable to modifications and are not yet as firmly established as in adult life.
The LancetSUICIDE PREVENTION BY THE SAMARITANS A Controlled Study of Effectiveness
73 Citations1977B. M. Barraclough
The trends in suicide-rates of county boroughs with Samaritan services have been compared with trends in matched control boroughs without Samarian services and the suicide-rate has decreased progressively and to the same extent.
BMJPredictive Factors in Open Myelomeningocele with Special Reference to Sensory Level
65 Citations1973Gillian Hunt, W. Lewin +2 more
A policy of confining operation to those patients with a reasonable chance of achieving independence would involve selecting for treatment a minority of all infants born with open myelomeningocele.
CancerEarly detection of malignant melanoma
65 Citations1976Martín C. Mihm, Thomas B. Fitzpatrick
Case examination of the skin is the first and foremost tool in the detection of skin cancer and appreciation of certain color changes, surface changes, and border changes in pigmented lesions is placed upon.
Archives of Disease in ChildhoodPerinatal cardiac arrest. Quality of the survivors.
64 Citations1975Hannes Steiner, G. A. Neligan
Twenty-two consecutive survivors of perinatal cardiac arrest have been followed to a mean age of 4 1/4 years, using methods of neurological and developmental assessment appropriate to their ages, and 4 showed evidence of gross, diffuse brain-damage.
BMJPerforation of chronic peptic ulcers after cimetidine.
63 Citations1977W. Angus Wallace, Charles M. Orr +1 more
PubMedCystic fibrosis detection by means of a test-strip.
63 Citations1975U Stephan, Elmar Busch +2 more
Journal of Epidemiology & Community HealthScreening for spina bifida cystica. A cost-benefit analysis.
63 Citations1976Spencer Hagard, F Carter +1 more
The costs and economic benefits are examined of introducing a programme for the mass-screening of pregnancies for the detection and abortion of fetuses with spina bifida cystica, and a benefit-cost index is derived.
Journal of Bone and Joint SurgeryMilwaukee brace correction of idiopathic scoliosis. A biomechanical analysis and a restrospective study
62 Citations1976T.P. Andriacchi, AB Schultz +2 more
The study suggests that careful adherence to mechanical principles in the use of a Milwaukee brace will result in successful treatment of more patients.
CancerFrequency of skin cancer and solar keratoses in a rural southern county as determined by population sampling
61 Citations1974Z. W. Zagula-Mally, E. William Rosenberg +1 more
The frequency of skin cancer and solar keratoses in a rural Tennessee county was surveyed using techniques of cluster sampling and raises questions about the practicality of their surgical treatment.
PubMed50,000 child-years of accidental injuries.
61 Citations1966Dean I. Manheimer, Joanna Dewey +2 more
BMJAcquired myopia in 11-year-old children.
60 Citations1977C S Peckham, P A Gardiner +1 more
Findings obtained at 7 years of age showed that superior educational attainments were already apparent before the onset of myopia, and at 11 years myopic children showed striking advantages in educational performance over their normal-sighted peers, as judged by tests of reading, arithmetic, and general ability.
The Journal of the American Dental AssociationPrevention and Control of Periodontal Disease
60 Citations1971John D. Suomi
In view of the recent widespread interest in plaque control, the Council on Dental Research deemed it appropriate to have a review prepared on the preventive aspects of periodontal disease.
New England Journal of MedicineSpecific Prophylaxis of Gonorrheal Ophthalmia Neonatorum
58 Citations1966Paul C. Barsam
American Journal of Public HealthA comparison of the health of index and subsequent babies born to school age mothers.
58 Citations1975James F. Jekel, Jennifer Harrison +3 more
Journal of GerontologyEmployment, Retirement, and Morale Among Older Women
58 Citations1976Philip Jaslow
Satistically significant differences remained after simultaneously isolating the effects of age, income, and health, lending tentative support to the hypothesis and suggesting that work may indeed have a salutary thought limited psychological influence among women in the post-65 years.
CancerPreliminary report of the lung cancer detection program in New York
58 Citations1977Myron R. Melamed, Betty J. Flehinger +5 more
It is suggested that a combination of chest X‐rays and sputum cytology can be more effective than either one alone in detecting early lung cancer.
British Journal of OphthalmologyEpidemiology of simple glaucoma and ocular hypertension.
57 Citations1972P. A. Graham
Four patients were studied who were in their twenties when the field defect was discovered and had other lesions which could have been spotted, such as abnormal blood sugar or vascular changes, and were by no means the highest in the population studied.
New England Journal of MedicineA Community Study of the Relation of Alpha<sub>1</sub>-Antitrypsin Levels to Obstructive Lung Diseases
56 Citations1975James O. Morse, Michael D. Lebowitz +2 more
The data militate strongly against the use of any quantitative determination of alpha1-antitrypsin as a test to identify subjects with moderate deficiency for the purpose of predicting later development of chronic respiratory disorders.
PubMedFetal alcohol syndrome. Experience with 41 patients.
54 Citations1976J W Hanson, Kenneth Lyons Jones +1 more
The LancetFOLLOW-UP OF 164 PATIENTS WITH BACTERIURIA OF PREGNANCY
53 Citations1968P. E. Gower, B. Haswell +2 more
There was no evidence to suggest that bacteriuria of pregnancy or acute pyelonephritis of pregnancy caused the renal radiological abnormalities, and the intravenous pyelograms of 82% showed no renal abnormality.
BMJClinical Trial of Iron Therapy on Psychomotor Function in Anaemic Women
51 Citations1970P C Elwood, Dafydd Hughes
There was no evidence of any beneficial effect of a rise in haemoglobin level on psychomotor function or on symptoms of anaemia, and anaemia is probably a rare cause of symptoms or impairment in psychom motor function in the community.
PubMedPresent knowledge of immunization against tuberculosis.
51 Citations1976Huyen Dam, K Toman +2 more
This is a selective review, which, after recalling some immunological aspects, analyses the present knowledge on the protective efficacy of BCG vaccination, the vaccination reactions and complications that may be observed, and current methods of vaccine production and control.
Journal of Occupational and Environmental MedicineOccupational Skin Cancer: A Review
50 Citations1975Edward A. Emmett
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