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Quantitation of HIV-1 RNA in Plasma Predicts Outcome after Seroconversion

Annals of Internal MedicinePublished 15 April 1995
John W. Mellors, Lawrence A. Kingsley, Charles R. Rinaldo, John A. Todd, Brad S. Hoo, Robert P. Kokka
Citations940
SJR quartileQ1
SJR score3.38
SNIP3.27

TL;DR

The objective was to compare plasma HIV-1 RNA with determinations of serum p24 antigen, neopterin, and 2-microglobulin levels and CD4+ T-cell counts as predictors of outcome in a cohort of homosexual men with documented HIV- 1 seroconversion.

Abstract

Plasma HIV-1 RNA is a strong, CD4+ T-cell-independent predictor of a rapid progression to AIDS after HIV-1 seroconversion.

Keywords

Immunology and MicrobiologyMedicine