Reliability, validity, and clinical correlates of apathy in Parkinson's disease
Journal of NeuropsychiatryPublished 1 May 1992
S E Starkstein, H S Mayberg, Thomas J. Preziosi, P Andrezejewski, R. Leiguarda, R G Robinson
Citations1,177
SJR quartileQ1
SJR score0.90
SNIP0.86
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TL;DR
Results suggest that apathy is a frequent finding in PD, is significantly associated with specific cognitive impairments, and may have a different mechanism than depression.
Abstract
The authors examined a consecutive series of 50 patients for the presence of apathy, depression, anxiety, and neuropsychological deficits using a neuropsychological battery that included a recently designed apathy scale. This scale was found to be reliable and valid in the diagnosis of apathy in patients with PD. Of patients in the study, 12% showed apathy as their primary psychiatric problem, and 30% were both apathetic and depressed. Patients with apathy (with or without depression), showed significantly more deficits in both tasks of verbal memory and time-dependent tasks. Results suggest that apathy is a frequent finding in PD, is significantly associated with specific cognitive impairments, and may have a different mechanism than depression.
Keywords
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