Rational Local Therapy for Breast Cancer
New England Journal of MedicinePublished 17 October 2002
Monica Morrow
Citations68
SJR quartileQ1
SJR score19.08
SNIP13.47
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TL;DR
In a 1976 lecture to the Society of Surgical Oncology, the late Jerome Urban lamented the loss of a rational approach to the treatment of breast cancer, which he thought had been replaced “by an em...
Abstract
In a 1976 lecture to the Society of Surgical Oncology, the late Jerome Urban lamented the loss of a rational approach to the treatment of breast cancer, which he thought had been replaced “by an emotional appeal to the patient's vanity. A great cry has been raised in the public media to save the breast, despite the long-term consequences.”1 In this issue of the Journal, Fisher and colleagues2 and Veronesi and colleagues3 describe the long-term outcomes of two pivotal randomized trials comparing breast-conserving surgery and mastectomy. These studies document how far our understanding of breast cancer has evolved since Urban's . . .
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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The scope of surgery should be correlated with the clinical and pathologic extent of disease in the individual patient with the aim of removing all disease present while preserving appearance and function—the main goal being removal of disease.