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Effect of Sabin Type 1 Poliomyelitis Vaccine Administered by Mouth to Newborn Infants

New England Journal of MedicinePublished 25 May 1961
Martha L. Lepow, Robert J. Warren, Nigel Gray, Virginia G. Ingram, Frederick C. Robbins
Citations74
SJR quartileQ1
SJR score19.08
SNIP13.47

TL;DR

The response of newborn infants to the feeding of Type 1 attenuated poliovirus vaccine (Sabin LSc-2 ab) is described and observations were made upon infants fed the same vaccine at three months of age.

Abstract

IT is the purpose of this report to describe the response of newborn infants to the feeding of Type 1 attenuated poliovirus vaccine (Sabin LSc-2 ab). For comparison, observations were also made upon infants fed the same vaccine at three months of age.This study was undertaken because there appear to be certain practical advantages in beginning immunization during the first few days of life. Active immunity might be achieved while the infant was still protected by antibody passively acquired from the mother, and thus there would be no interval when the child would be susceptible to paralytic disease. If . . .

Keywords

Immunology and MicrobiologyMedicine