THE EFFECT OF WEIGHT LOSS ON SEX STEROID SECRETION AND BINDING IN MASSIVELY OBESE WOMEN
Clinical EndocrinologyPublished 1 August 1981
Peter Kopelman, Nicholas J. White, T. R. E. Pilkington, S.L. Jeffcoate
Citations77
SJR quartileQ2
SJR score1.01
SNIP1.11
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TL;DR
It is concluded that body weight and fat are important determinants of sex steroid secretion and binding and thus influence menstrual function.
Abstract
We have previously reported increased testosterone and androstenedione concentrations and decreased sex hormone binding globulin (SHBG) concentrations in the plasma of massively obese women. We now report that these plasma hormone concentrations return to normal in twelve of the same women after substantial weight reduction and these changes are associated with more normal menstrual cycles. We conclude that body weight and fat are important determinants of sex steroid secretion and binding and thus influence menstrual function.
Keywords
Medicine
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