Blood pressure reductions with exercise and sodium restriction in postmenopausal women with elevated systolic pressure: role of arterial stiffness
Journal of the American College of CardiologyPublished 1 August 2001
Douglas R. Seals, Hirofumi Tanaka, Christopher M. Clevenger, Kevin D. Monahan, M. J. Reiling, William R. Hiatt
Citations187
SJR quartileQ1
SJR score9.02
SNIP6.30
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TL;DR
Moderate SR lowers SBP and PP in postmenopausal women with elevated baseline levels more than does daily walking, and the greater blood pressure reductions with SR may be mediated in part by a decrease in the stiffness of the large elastic arteries.
Abstract
Moderate SR lowers SBP and PP in postmenopausal women with elevated baseline levels more than does daily walking. The greater blood pressure reductions with SR may be mediated in part by a decrease in the stiffness of the large elastic arteries.
Keywords
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BMJBy how much does dietary salt reduction lower blood pressure? III--Analysis of data from trials of salt reduction.
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403 Citations1998Paolo Verdecchia, Giuseppe Schillaci +4 more
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American Heart JournalElevated systolic blood pressure and risk of cardiovascular and renal disease: Overview of evidence from observational epidemiologic studies and randomized controlled trials
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HypertensionNational High Blood Pressure Education Program Working Group Report on Hypertension in the Elderly. National High Blood Pressure Education Program Working Group.
286 Citations1994
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American Heart JournalAssessment of the daily blood pressure load as a determinant of cardiac function in patients with mild-to-moderate hypertension
277 Citations1989William B. White, Holley M. Dey +1 more
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Journal of Human HypertensionThe effectiveness of exercise training in lowering blood pressure: a meta-analysis of randomised controlled trials of 4 weeks or longer
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