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The ProDom database of protein domain families: more emphasis on 3D

Nucleic Acids ResearchPublished 17 December 2004Open access
C. Bru
Citations355
SJR quartileQ1
SJR score7.78
SNIP4.71
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TL;DR

ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics, has been developed.

Abstract

ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (3D) information from the SCOP database; a completely redesigned web interface (http://www.toulouse.inra.fr/prodom.html); visualization of ProDom domains on 3D structures; coupling of ProDom analysis with the Geno3D homology modelling server; Bayesian inference of evolutionary scenarios for ProDom families. In addition, we have developed ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics.

Keywords

Biochemistry, Genetics and Molecular Biology