Specific abnormalities in serotonin release in the prefrontal cortex of isolation-reared rats measured during behavioural performance of a task assessing visuospatial attention and impulsivity
PsychopharmacologyPublished 1 November 2002
Jeffrey W. Dalley, David Theobald, Erlick Pereira, Peng Li, Trevor W. Robbins
Citations185
SJR quartileQ1
SJR score1.16
SNIP0.97
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TL;DR
These findings highlight a rather specific deficit in 5-HT release in the prefrontal cortex of isolation-reared rats, although this appears not to affect visual attentional function.
Abstract
These findings highlight a rather specific deficit in 5-HT release in the prefrontal cortex of isolation-reared rats, although this appears not to affect visual attentional function. Rather, these data may be relevant to reduced impulsiveness of isolation-reared rats on the five-choice task. These findings are important in the context of animal models of attentional disturbances in schizophrenia.
Keywords
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