Prevention of Relapse Following Cognitive Therapy vs Medications in Moderate to Severe Depression
Archives of General PsychiatryPublished 1 April 2005
Steven D. Hollon, Robert J. DeRubeis, Richard C. Shelton, Jay D. Amsterdam, Ronald M. Salomon, John P. O’Reardon
Citations724
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Cognitive therapy has an enduring effect that extends beyond the end of treatment and seems to be as effective as keeping patients on medication.
Abstract
Cognitive therapy has an enduring effect that extends beyond the end of treatment. It seems to be as effective as keeping patients on medication.
Keywords
PsychologyMedicine
Journal of Neurology Neurosurgery & PsychiatryA RATING SCALE FOR DEPRESSION
32,633 Citations1960M. Hamilton
The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
Wiley series in probability and statisticsStatistical Methods for Rates and Proportions
18,048 Citations2003Joseph L. Fleiss, Bruce Levin +1 more
Analysis of Survival Data
5,999 Citations2018D. R. Cox, David Oakes
Archives of General PsychiatryNational Institute of Mental Health Treatment of Depression Collaborative Research Program
2,324 Citations1989Irene Elkin
There was limited evidence of the specific effectiveness of interpersonal psychotherapy and none for cognitive behavior therapy, but Superior recovery rates were found for both interpersonal Psychotherapy and imipramine plusclinical management, as compared with placebo plus clinical management.
Archives of General PsychiatryConceptualization and Rationale for Consensus Definitions of Terms in Major Depressive Disorder
1,940 Citations1991Ellen Frank
It is concluded that research on depressive illness would be well served by greater consistency in the definition change points in the course of illness, and proposes an internally consistent, empirically defined conceptual scheme for the terms remission, recovery, relapse, and recurrence.
Archives of General PsychiatryThe Longitudinal Interval Follow-up Evaluation
1,637 Citations1987Martin B. Keller
The Longitudinal Interval Follow-up Evaluation (LIFE) is an integrated system for assessing the longitudinal course of psychiatric disorders that consists of a semistructured interview, an Instruction booklet, a coding sheet, and a set of training materials.
Behaviour Research and TherapyHow does cognitive therapy prevent depressive relapse and why should attentional control (mindfulness) training help?
1,345 Citations1995John D. Teasdale, Zindel V. Segal +1 more
An information-processing analysis of depressive maintenance and relapse is used to define the requirements for effective prevention, and to propose mechanisms through which cognitive therapy achieves its prophylactic effects.
Archives of General PsychiatryCognitive Therapy vs Medications in the Treatment of Moderate to Severe Depression
965 Citations2005Robert J. DeRubeis, Steven D. Hollon +9 more
Cognitive therapy can be as effective as medications for the initial treatment of moderate to severe major depression, but this degree of effectiveness may depend on a high level of therapist experience or expertise.
Archives of General PsychiatryCourse of Depressive Symptoms Over Follow-up
514 Citations1992M. Tracie Shea
The major finding of this study is that 16 weeks of these specific forms of treatment is insufficient for most patients to achieve full recovery and lasting remission.
Gothic.netTreatment and Prevention of Depression
508 Citations2002Steven D. Hollon, Michael E. Thase +1 more
Combined treatment with medication and CBT appears to be as efficacious as treatment with medications alone and to retain the enduring effects of CBT, and there are indications that the same strategies used to reduce risk in psychiatric patients following successful treatment can be used to prevent the initial onset of depression in persons at risk.
Archives of General PsychiatryDifferential Relapse Following Cognitive Therapy and Pharmacotherapy for Depression
485 Citations1992Mark D. Evans
It appears that providing cognitive therapy during acute treatment prevents relapse, and whether this preventive effect extends to recurrence remains to be determined.
Archives of General PsychiatryCognitive Therapy and Pharmacotherapy for Depression
443 Citations1986Anne D. Simons
Patients with relatively high levels of remaining depressive symptoms on completion of treatment relapsed more often than those who had little or no residual depression and had significantly higher scores on a measure of dysfunctional attitudes at treatment termination.
Archives of General PsychiatryDepressed Outpatients Treated With Cognitive Therapy or Pharmacotherapy
378 Citations1981Mária Kovács
Journal of Affective DisordersA two-year naturalistic follow-up of depressed patients treated with cognitive therapy, pharmacotherapy and a combination of both
340 Citations1986I. M. Blackburn, Kate M. Eunson +1 more
The number of individuals who relapsed at some point over the 2 years was significantly higher in the pharmacotherapy group than in either of the cognitive therapy groups.
American Journal of PsychiatryContinuation drug therapy for major depressive episodes: how long should it be maintained?
297 Citations1986Robert F. Prien, David J. Kupfer
Findings indicate that withdrawal of continuation drug treatment of depressive episodes is safe only after the patient has been free of significant symptoms for 16 to 20 weeks and that focusing on mild as well as severe symptoms is critical in this decision.
American Journal of PsychiatryOptimal Length of Continuation Therapy in Depression: A Prospective Assessment During Long-Term Fluoxetine Treatment
203 Citations1998Frederick W. Reimherr, Jay D. Amsterdam +8 more
Relapse rates were lower among the patients who continued to take fluoxetine compared with those transferred to placebo in both the first interval, after 24 total weeks of treatment, and the second, after 38 total weeks, which were not significantly different between the groups.
Cognitive Therapy and ResearchOn second thought: Where the action is in cognitive therapy for depression
188 Citations1989Jacques P. Barber, Robert J. DeRubeis
British Actuarial JournalModelling Survival Data in Medical Research. By D. Collett (Chapman & Hall, 1994) £19.99
123 Citations1995Amy MacDonald
This new book provides an excellent introduction at a level that is very suitable for actuaries who have studied statistics at about the level of Subject Cl, and will give the reader a very useful guide in trying to follow the more advanced literature.
Behavior TherapyA cost-effectiveness analysis of cognitive behavior therapy and fluoxetine (prozac) in the treatment of depression
109 Citations1997David O. Antonuccio, Michael R. Thomas +1 more
The outcome studies are considered as the basis for a cost-effectiveness comparison of drugs and psychotherapy in the treatment of unipolar depression and shows that over a 2-year period, fluoxetine alone may result in 33% higher expected costs than individual CBT treatment and the combination treatment might result in 23% higher costs than CBT alone.
Behavior TherapyTreatment guidelines for major depressive disorder
65 Citations2001Steven D. Hollon, Richard C. Shelton
The revised guideline clearly improves upon the original in many respects and is more closely tied to the empirical literature, but still understates the case for the empirically supported psychosocial interventions.
