The structure-activity relationship in several schistosomicidal compounds.
PubMedPublished 1 January 1961Open access
R. Gönnert
Citations24
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Further chemical and biological investigations have confirmed the hypothesis that the schistosomicidal activity of this chemical group depends on the structure-activity relationship to other groups of compounds.
Keywords
Immunology and Microbiology
Annals of Tropical Medicine and ParasitologyExperimental Studies on the Therapy of Schistosomiasis
110 Citations1948Walter Kikuth, R. Gönnert
Transactions of the Royal Society of Tropical Medicine and HygieneClinical test of the miracil compound 27T51
8 Citations1954J. Newsome
The lucanthone (“miracil”) compound 27T51, which was found to be active against Schistosoma mansoni in baboons, proved to be unsuitable for human treatment and a single dose caused severe nerve deafness and repeated doses were considered impracticable.
Journal of ParasitologyChemotherapy of Experimental Schistosomiasis. I. Drug Activity and Mode of Action of a New Thioxanthone Derivative
7 Citations1958Z. Brener, J. Pellegrino
The results obtained in mice experimentally infected with S. inansoni and treated with a new thioxanthone derivative are reported, along with some observations concerning the mode of drug action.
