ACTION OF DIAMOX AND AMMONIUM CHLORIDE ON FORMATION OF AQUEOUS HUMOUR
British Journal of OphthalmologyPublished 1 February 1957Open access
M. E. Langham, P. M. Lee
Citations65
SJR quartileQ1
SJR score1.81
SNIP1.83
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TL;DR
The investigation was undertaken to establish the cause of the decrease in intra-ocular pressure induced in normal rabbits by 2-acetylamino-1, 3, 4 thiadiazole 5-sulphonamidet, an inhibitor of the enzyme carbonic anhydrase to assess whether the intra-cular dynamics of normal and pathological eyes are affected in a similar manner and to a comparable extent.
Archives of OphthalmologyTONOGRAPHIC METHOD FOR MEASURING THE FACILITY AND RATE OF AQUEOUS FLOW IN HUMAN EYES
270 Citations1950W. M. GRANT
It is believed that the method described here provides a means of discerning in what measure changes in intraocular pressure are due to change in facility of outflow or tochange in net rate of aqueous humor formation.
British Journal of OphthalmologyInfluence of the Sympathetic Nervous System on the Intra-Ocular Pressure and Vascular Circulation of the Eye
98 Citations1952D. P. Greaves, E. S. Perkins
The effects on the intraocular pressure of cutting and stimulating the cervical sympathetic nerves in cats and rabbits and the appearance in vivo of the aqueous veins and choroidal circulation are described.
Archives of OphthalmologyPosterior and Anterior Chamber Aqueous Humor Formation
88 Citations1955V. Everett Kinsey, E. C. Palm +1 more
Aqueous humor was once thought to be a dialysate of plasma, or to be secreted as such by the ciliary body in a manner analogous to secretion of saliva by the salivary gland, but a theory was evolved which envisaged these two processes, secretion and diffusion (dialysis), as taking place simultaneously.
Archives of ophthalmologyA UNIFIED CONCEPT OF AQUEOUS HUMOR DYNAMICS AND THE MAINTENANCE OF INTRAOCULAR PRESSURE
66 Citations1950V. Everett Kinsey
Aqueous humor dynamics deals with the movement of various components of the plasma into and out of the posterior and anterior chambers of the eye and with the forces that result from this movement.
The Journal of General PhysiologyTHE CHEMICAL COMPOSITION AND THE OSMOTIC PRESSURE OF THE AQUEOUS HUMOR AND PLASMA OF THE RABBIT
63 Citations1951V. Everett Kinsey
The concentration of all the major components of the aqueous humor and plasma has been determined by chemical analysis on fluid samples obtained from unanesthetized rabbits at approximately the same time.
The Journal of General PhysiologySTUDIES OF GAS AND ELECTROLYTE EQUILIBRIA IN THE BLOOD
57 Citations1927A. Baird Hastings, Harald A. Salvesen +2 more
Distribution ratios of HCO3, Cl, Na, and H+ deviated from unity as predicted by the Gibbs-Donnan law for similar heterogeneous systems after equilibration across collodion membranes showed distributions similar to those between serum and edema fluid in vivo.
The American Journal of MedicineRespiratory and renal effects of a carbonic anhydrase inhibitor (diamox) on acid-base balance in normal man and in patients with respiratory acidosis
49 Citations1955Morton Galdston
Intensification of acidosis by diamox-induced fall in plasma bicarbonate in the chronic emphysema patients did not alter their degree of respiratory depression during inhalation of 100 per cent oxygen and the response of one such patient was not less depressed when there was a concomitant reduction in the level of arterial pCO 2 .
The Journal of PhysiologyThe osmotic pressure of the aqueous humour in the normal and glaucomatous eye
36 Citations1938G. H. Benham, W. S. Duke‐Elder +1 more
Archives of OphthalmologyEFFECT OF ACETAZOLEAMIDE (DIAMOX) ON CARBONIC ANHYDRASE ACTIVITY OF ANTERIOR UVEA OF THE RABBIT EYE
36 Citations1954Harold D. Green, S. A. CAPPER +2 more
It was deemed of fundamental importance, therefore, to determine whether the administration of acetazoleamide affected the carbonic anhydrase activity of the ciliary body and iris.
The Journal of PhysiologyChanges in ionic distribution following dialysis of aqueous humour against plasma
31 Citations1949H. Davson, W. S. Duke‐Elder +1 more
Archives of OphthalmologyCarbonic Anhydrase and the Elaboration of Bicarbonate Ion in the Rabbit Eye
29 Citations1955Harold D. Green, Carol A. Bocher +4 more
The results show that the elaboration and active transfer of bicarbonate ions into the aqueous humor are not mediated by the carbonic anhydrase of the anterior uvea of the normal rabbit eye.
Canadian Medical Association JournalFactors Affecting the Distribution of Electrolytes, Water and Gases in the Animal Body
27 Citations1927A. T. Cameron
Central and peripheral pulmonary mucociliary clearance was assessed by tantalum bronchography and serial chest roentgenograms in dogs and thiopental, 25 mg/kg, did not change clearance from awake values.
The Journal of PhysiologyThe transfer of l‐ascorbic acid and dehydro‐l‐ascorbic acid into the aqueous humour of the rabbit and cat
17 Citations1950M. E. Langham
Experiments on the dynamic aspects of the transfer from blood to aqueous humour of ascorbic acid and of its reversibly oxidized form, dehydro-ascorbic acid will be described.
British Journal of OphthalmologyCORRELATION OF THE SYSTEMIC AND INTRA-OCULAR EFFECTS OF DIAMOX
16 Citations1956Donald Campbell, E. L. Tonks +1 more
Whether it is desirable to use repeated doses in the treatment of glaucoma or whether Diamox would be more wisely employed in single doses at intervals of several days with miotics in the interim is considered.
The Journal of PhysiologyThe use of ascorbic acid to measure the rate of flow of plasma through the ciliary processes
13 Citations1955Maurice E. Langham
The use of ascorbic acid is proposed to estimate the rate of flow of plasma through the ciliary processes in a manner analogous to the use of p-aminohippuric acid in studies of renal function.