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Persistent Immunity Following Enders Live, Attenuated Measles-Virus Vaccine Given with Human Immune Globulin

New England Journal of MedicinePublished 2 August 1962
J Stokes, M. R. Hilleman, Robert E. Weibel, Eugene B. Buynak, R. Halenda
Citations15
SJR quartileQ1
SJR score19.08
SNIP13.47

TL;DR

Findings are presented showing persistent and undiminished immunity against measles for at least a year after administration of live measles-virus vaccine with human immune globulin.

Abstract

PREVIOUS studies by various workers1 2 3 4 5 6 7 8 9 10 11 12 have established the high level of efficacy of the Enders live measles-virus vaccine given alone or in combination with human immune globulin. Such efficacy is expressed in terms both of development of antibody after vaccination and of protection against natural measles in epidemics.One of the important problems that remain is the assessment of durability of immunity after vaccination. This report presents findings showing persistent and undiminished immunity against measles for at least a year after administration of live measles-virus vaccine with human immune globulin.Materials and MethodsClinical Populations and Vaccination ProcedurePrevious reports . . .

Keywords

Immunology and MicrobiologyMedicine