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The passage of orally fed proteins from mother to foetus in the rat

Comparative Biochemistry and Physiology Part A PhysiologyPublished 1 January 1984
Gudrun Dahl, Esbjörn Telemo, Björn Weström, I Jakobsson, T Lindberg, Börje W. Karlsson
Citations44

TL;DR

The results imply that a variety of dietary proteins, still immunoprecipitable, are able to cross the materno-foetal barriers to be detected in the foetal circulation, where they may influence the maturation of the immune system of the foetus.

Abstract

Pregnant rats were orally fed with a mixture of bovine IgG, bovine albumin, ovalbumin and beta-lactoglobulin. Using immunoprecipitation methods, these proteins were detected in the maternal blood serum, urine and uterine fluids, and also in the foetal blood serum and the amniotic fluid. The results imply that a variety of dietary proteins, still immunoprecipitable, are able to cross the materno-foetal barriers to be detected in the foetal circulation, where they may influence the maturation of the immune system of the foetus.

Keywords

Biochemistry, Genetics and Molecular BiologyNursing