Pyridoxine-responsive anaemia determined by an X-linked gene.
Journal of Medical GeneticsPublished 1 March 1966Open access
M. W. Elves, M. S. Bourne, M. C. G. Israëls
Citations14
SJR quartileQ1
SJR score1.62
SNIP1.40
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TL;DR
Details of a family in which a hereditary pyridoxine-responsive anaemia occurred are reported, and the haematological picture is of a hypochromic anaemia with microcytic red cells which show anisocytosis and poikilocyTosis and often target cells.
Keywords
Materials ScienceBiochemistry, Genetics and Molecular Biology
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332 Citations1957W. N. M. Ramsay
The author's original method for the determination of iron in plasma or serum has been modified so as to eliminate filtration and give other advantages.
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Five cases manifesting a distinctive form of refractory hypochromic anemia complicated consistently by the later development of hemochromatosis have been studied in an attempt to define furelessness.
BloodPyridoxine-Responsive Anemia: Report of 2 Cases in Brothers and a Review of the Literature
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The clinical and laboratory findings in two brothers with severe anemia were very similar in both cases, and evidence that at least one of them suffered from a pyridoxine-responsive anemia is presented, and increased requirement of vitamin B6 seems to be the most likely possibility.
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The discontinuous buffer system enables the detection of hemoglobin A2 in small samples of hemolysate and resolution of abnormal hemoglobins is superior to that in barbital or Tris-EDTA-borate buffer alone.
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