Monosynaptic excitation of principal cells in the lateral geniculate nucleus by corticofugal fibers
Brain ResearchPublished 1 February 1982
Gunilla Ahlsén, Kirsty Grant, Sar M
Citations96
SJR quartileQ2
SJR score0.85
SNIP0.72
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Electrical stimulation of the primary visual cortex evoked long latency EPSPs in X and Y principal cells of the cat's lateral geniculate nucleus, and it was revealed that these EPSPs were mediated monosynaptically to principal cells by slowly conducting corticogeniculate fibers.
Abstract
Electrical stimulation of the primary visual cortex evoked long latency EPSPs in X and Y principal cells of the cat's lateral geniculate nucleus. An extrapolation procedure was used to reveal that these EPSPs were mediated monosynaptically to principal cells by slowly conducting corticogeniculate fibers. A similar type of excitation was observed in intrageniculate interneurons.
Keywords
Neuroscience
The Journal of PhysiologySustained and transient neurones in the cat's retina and lateral geniculate nucleus
1,048 Citations1971B. G. Cleland, Mark W. Dubin +1 more
Cat retinal ganglion cells may be subdivided into sustained and transient response‐types by the application of a battery of simple tests based on responses to standing contrast, fine grating patterns, size and speed of contrasting targets, and on the presence or absence of the periphery effect.
The Journal of PhysiologyIntegrative action in the cat's lateral geniculate body
788 Citations1961David H. Hubel, T. N. Wiesel
Receptive fields of geniculate receptive fields resembled those of retinal ganglion cells, having an excitatory ('on') centre and inhibitory preriphery, or reverse, and cells with receptive fields within or near the area centralis tended to have smaller field centres and stronger suppression by the receptive field periphery than cells with their fields situated in more peripheral regions of the retina.
The Journal of Comparative NeurologyThe projections of cells in different layers of the cat's visual cortex
728 Citations1975Charles D. Gilbert, James P. Kelly
The projection of cells in different layers of several cortical visual areas in the cat were studied using the method of retrograde transport of horseradish peroxidase, indicating a remarkable specificity in the projections of the cortical layers.
Journal of NeurophysiologyOrganization of visual inputs to interneurons of lateral geniculate nucleus of the cat
321 Citations1977Mark W. Dubin, B. G. Cleland
It is suggested that the intrageniculateinterneurons are involved in precise, spatially organized inhibition and that the perigeniculate interneuron are part of a more general, diffuse inhibitory system that modulates LGN excitability.
The Journal of PhysiologySynaptic actions of single interneurones mediating reciprocal Ia inhibition of motoneurones
295 Citations1972E. Jankowska, William J. Roberts
The interneurones were found to produce unitary monosynapticIPSPs in those motoneurones in which disynaptic IPSPs are evoked by the group Ia afferents whichmonosynaptically excite the interneerones.
Experimental Brain ResearchFunctional organization of the corticofugal system from visual cortex to lateral geniculate nucleus in the cat
241 Citations1978Tadaharu Tsumoto, O. Creutzfeldt +1 more
It is concluded that the corticofugal excitatory effect is transmitted through monosynaptic links from VC neurons located in layer VI (complex cell) to LGN relay neurons (mostly sustained-cell) and this system is organized in a precise topographical manner.
Proceedings of the Royal Society of London. Series B, Biological sciencesAn electron microscopic study of the mode of termination of cortico-thalamic fibres within the sensory relay nuclei of the thalamus
225 Citations1969Edward G. Jones, T.P.S. Powell
Findings indicate that the terminals of cortico-thalamic fibres belong to the small dark group of axon terminals described in the normal nuclei, but the persistence of many small dark terminals after total hemidecortication suggests that others have a subcortical origin.
The Journal of PhysiologyInhibitory mechanisms in lateral geniculate nucleus of rat
163 Citations1966W. J. Burke, Ann Jervie Sefton
An examination was made of the mechanisms responsible for the inhibition of synaptic transmission through the lateral geniculate nucleus of the rat following a single shock to the optic nerve.
Brain ResearchThe role of visual cortex for binocular interactions in the cat lateral geniculate nucleus
161 Citations1977F. Schmielau, Wolf Singer
It is suggested that corticofugal fibers are excitatory to relay cells and in addition reduce the efficiency of intrageniculate inhibitory mechanisms.
Brain ResearchSynaptic organization of inhibitory pathways to principal cells in the lateral geniculate nucleus of the cat
154 Citations1982Sivert Lindstro ̈m
The Journal of Comparative NeurologyThe pattern of projection of cortical areas 17, 18, and 19 onto the laminae of the dorsal lateral geniculate nucleus in the cat
125 Citations1975B. V. Updyke
The projection of cortical areas 17, 18, and 19 onto the laminar part of the dorsal lateral geniculate nucleus was investigated with degeneration methods and with the autoradiographic axon tracing method and results suggested that the area 17 projection is heavier and more uniform than the projections from areas 18 and 19.
ScienceStructure of Physiologically Identified X and Y Cells in the Cat's Lateral Geniculate Nucleus
89 Citations1979Michael J. Friedlander, C. S. Lin +1 more
Horseradish peroxidase injected into 18 single, physiologically identified geniculate X and Y cells permitted a detailed morphological correlate to be determined for the physiological properties of each neuron.