Amitriptyline and EEG Sleep in Depressed Patients: I. Drug Effect
SLEEPPublished 1 September 1978Open access
David J. Kupfer, Duane G. Spiker, Patricia A. Coble, R.J. McPartland
Citations75
SJR quartileQ1
SJR score1.80
SNIP1.63
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TL;DR
The incomplete tolerance of the drug on certain REM sleep variables enhances the understanding of amitryptyline effects on the EEG sleep of depressed patients.
Abstract
Frank Harper tells J. Roy Kerr that the interview published in the New York Call is a fabrication and satire.
Keywords
Neuroscience
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The development and initial reliability studies of a set of specific diagnostic criteria for a selected group of functional psychiatric disorders, the Research Diagnostic Criteria (RDC), indicate high reliability for diagnostic judgments made using these criteria.
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The use of a single 25 mg dose of amitriptyline on the day following partial differential REM sleep deprivation PDRD was attended by a significant decrease in REM sleep and by a rebound elevation of REM sleep during the following recovery night.
