A Prospective Study of Psychosocial Morbidity in Adult Bone Marrow Transplant Recipients
PsychosomaticsPublished 1 July 1994
Peter Jenkins, H. M. O. Lester, Julie Alexander, Jack Whittaker
Citations64
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
In contrast to other studies, little influence was found for psychiatric illness on physical outcome variables, but they did affect psychosocial outcome.
Abstract
Forty recipients of bone marrow transplantation were recruited prospectively and assessed pretransplant, at 1 month postdischarge, and at 6 months postdischarge between 1989 and 1990. Assessments included a psychiatric interview, a variety of standardized questionnaires (Hospital Anxiety and Depression Scale, Mental Attitude to Cancer Scale, Psychosocial Adjustment to Illness Scale), and a standardized diagnostic interview. The influence of factors such as depression and anxiety upon length of stay, survival, psychosocial adjustment, and negative prognostic attitudes were examined. In contrast to other studies, little influence was found for psychiatric illness on physical outcome variables, but they did affect psychosocial outcome. The implications of these findings are discussed.
Keywords
Medicine
Acta Psychiatrica ScandinavicaThe Hospital Anxiety and Depression Scale
46,617 Citations1983A. S. Zigmond, R. P. Snaith
It is suggested that the introduction of the scales into general hospital practice would facilitate the large task of detection and management of emotional disorder in patients under investigation and treatment in medical and surgical departments.
The British Journal of PsychiatryCross-cultural Feasibility, Reliability and Sources of Variance of the Composite International Diagnostic Interview (CIDI)
839 Citations1991Hans‐Ulrich Wïttchen, L Robins +4 more
The CIDI was judged to be acceptable for most subjects and was appropriate for use in different kinds of settings, and no significant numbers of diagnostic disconcordances were found with lifetime, six-month, and four-week time frames.
PubMedMental adjustment to cancer: its measurement and prognostic importance.
192 Citations1987Steven Greer, Martin Watson
Preliminary results suggest that the MAC scale is a suitable, easily replicable method of measuring adjustment to cancer in studies of large numbers of patients.
PsychosomaticsDepressed Mood and Other Variables Related to Bone Marrow Transplantation Survival in Acute Leukemia
160 Citations1991Eduardo A. Colón, Allan L. Callies +2 more
Routine psychiatric evaluations of 100 adult patients undergoing allogeneic bone marrow transplantation for acute leukemia were reviewed to examine the possible relationship of psychiatric and psychosocial factors to duration of survival following the procedure.
TransplantationADAPTATION OF ADULT BONE MARROW TRANSPLANT RECIPIENT LONG-TERM SURVIVORS
118 Citations1986Deane L. Wolcott, David K. Wellisch +2 more
The findings indicate that about 75% of BMT recipient long-term survivors are doing well from a psychosocial as well as a medical standpoint, that the recipient-donor relationship may be sensitive to any changes in the recipient's status, and that 15–20% ofBMT recipient survivors report a degree of psychological distress that might benefit from specific psychological/psychiatric intervention.
PubMedLongitudinal assessment of psychosocial functioning of adult survivors of allogeneic bone marrow transplantation.
58 Citations1989Michael A. Andrykowski, P J Henslee +1 more
Results indicated little change in functioning with the passage of time, suggesting that most patients might achieve a ceiling level of functioning within a couple of years post-BMT, and further recovery of psychosocial functioning is likely to be minimal.
PubMedPsychological aspects of bone marrow transplantation: a retrospective study of 17 long-term survivors.
56 Citations1988M. W. Hengeveld, R B Houtman +1 more
Although the patients were overwhelmingly positive about the information and support they had received, an important number of them felt inadequately prepared for the emotional and sexual problems they had to face in the first period after discharge.
PsychosomaticsA Retrospective Study of Psychosocial Morbidity in Bone Marrow Transplant Recipients
55 Citations1991Peter Jenkins, A. Linington +2 more
Overall, patients demonstrated adjustment comparable with other medical patients, and a high prevalence of depression was shown to be associated with impaired function.
Heinemann Medical eBooksPsychological therapy for patients with cancer
53 Citations1989Stirling Moorey, Stephen Greer
PsychosomaticsPsychotropic Drug Use in the Medically Ill
28 Citations1991Alan Stoudemire, Michael G. Moran +1 more
Practical considerations in using psychotropic medications in medical-surgical patients--particularly those who are elderly or medically debilitated--will receive special emphasis.
PsychosomaticsPsychotropic Drug Use in the Medically Ill
22 Citations1990Alan Stoudemire, Michael G. Moran +1 more
This overview, published in two parts, discusses six major classes of psychotropic medications and examines their use in the setting of specific types of medical illnesses and practical considerations in using psychotrop medications in medical-surgical patients.
Current status of bone marrow transplantation
20 Citations1984E. Donnall Thomas
Based on studies in murine systems, bone marrow transplantation was undertaken in human patients in the late 1950s and early 1960s and the finding that marrow grafts between DLA-matched canine littermates resulted in a high proportion of long-term survivors was particularly important.
Human PathologyCurrent status of bone marrow transplantation
10 Citations1981G. Joanne Carlson, John H. Kersey
PubMedCurrent role and status of bone marrow transplantation.
1 Citations1989Malcolm K. Brenner, H. G. Prentice
Improvements in the understanding of the immunobiology of bone marrow transplantation are discussed and how the availability of recombinant growth factors for the haemopoietic and immune systems and the introduction of immunomodulatory monoclonal antibodies are beginning to make a major impact on the practice and outcome of the procedure are described.