Multiresolution elastic matching
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TL;DR
Results show that all normal brains, at least at a certain level of representation, have the same topological structure, but may differ in shape details, and the matching process can account for these differences.
Abstract
Matching of locally variant data to an explicit 3-dimensional pictorial model is developed for X-ray computed tomography scans of the human brain, where the model is a voxel representation of an anatomical human brain atlas. The matching process is 3-dimensional without any preference given to the slicing plane. After global alignment the brain atlas is deformed like a piece of rubber, without tearing or folding. Deformation proceeds step-by-step in a coarse-to-fine strategy, increasing the local similarity and global coherence. The assumption underlying this approach is that all normal brains, at least at a certain level of representation, have the same topological structure, but may differ in shape details. Results show that we can account for these differences.
