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Comparison of oral etoposide and standard intravenous multidrug chemotherapy for small-cell lung cancer: a stopped multicentre randomised trial

The LancetPublished 1 August 1996
D.J. Girling
Citations224
SJR quartileQ1
SJR score12.11
SNIP22.72

TL;DR

Oral etoposide alone is inferior to standard intravenous multidrug chemotherapy in the palliative treatment of patients with SCLC and poor performance status and should no longer be used in the treatment of such patients.

Abstract

Oral etoposide 50 mg twice daily for 10 days every 3 weeks for four cycles is inferior to standard intravenous multidrug chemotherapy in the palliative treatment of patients with SCLC and poor performance status. Oral etoposide alone should no longer be used in the treatment of such patients.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology