Cor Pulmonale Due to Adenoidal or Tonsillar Hypertrophy or Both in Children
CHEST JournalPublished 1 January 1988
Shaul Sofer, Elliott Weinhouse, Asher Tal, Kenneth L. Wanderman, Giora Margulis, Alberto Leiberman
Citations100
SJR quartileQ1
SJR score1.83
SNIP1.83
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Four children, aged 1 to 3 1/2, were first seen with cor pulmonale, pulmonary edema and severe respiratory distress due to chronic upper airway obstruction secondary to adenoidal or tonsillar hypertrophy or both; all four children improved following surgery.
Abstract
Four children, aged 1 to 3 1/2, were first seen with cor pulmonale, pulmonary edema and severe respiratory distress due to chronic upper airway obstruction secondary to adenoidal or tonsillar hypertrophy or both. Arterial blood gas values, electrocardiograms and chest x-ray films were compatible with cor pulmonale. Echocardiography (four cases) and radionuclide angiography (two cases) showed severe right ventricular and right atrial dilation with reduced right ventricular ejection fraction. Following surgery, all four children improved; their echocardiographic and radionuclide findings returned to normal. Cardiac catheterization, traditionally performed in such cases, was unnecessary. The diagnosis and follow-up of this syndrome are adequately performed noninvasively.
Keywords
Medicine
MedicineHIGH ALTITUDE PULMONARY EDEMA
285 Citations1961Herbert N. Hultgren, Warren B. Spickard +2 more
New England Journal of MedicineMechanical Forces Producing Pulmonary Edema in Acute Asthma
259 Citations1977S. Alex Stalcup, Robert B. Mellins
The Journal of PediatricsHypoventilation and cor pulmonale due to chronic upper airway obstruction
234 Citations1965Victor Menashe, Cyrus Farrehi +1 more
A syndrome of chronic upper airway obstruction, hypoventilation, and cor pulmonale seen in 2 children both manifested varying degrees of CO 2 retention, pulmonary hypertension, and right ventricular hypertrophy.
PEDIATRICSCHRONIC NASOPHARYNGEAL OBSTRUCTION AS A CAUSE OF CARDIOMEGALY, COR PULMONALE, AND PULMONARY EDEMA
191 Citations1966Mary Jane Luke, Ali Abouei Mehrizi +2 more
The problem of chronic upper airway obstruction caused by tremendously enlarged tonsils and adenoids in children warrants further investigation and more widespread recognition as being potentially dangerous from cardiorespiratory standpoints.
The LancetPATHOGENESIS OF NEUROGENIC PULMONARY ŒDEMA
186 Citations1975James Theodore, E D Robin
After the transient systemic and pulmonary vascular hypertension subside, the patient is left with abnormal pulmonary capillary permeability, so that pulmonary oedema persists in the face of normal haemodynamic and cardiac function.
American Journal of Physiology-Heart and Circulatory PhysiologyLeft ventricular dimensions and function during right ventricular pressure overload
68 Citations1982F R Badke
It is concluded that RV pressure overload displaces the septum toward the LV free wall; acutely this displacement is primarily at end diastole, but chronically it occurs at end systole as well, maintaining the sePTal contribution to LV ejection.
Clinics in Chest MedicineEffects of Positive and Negative Pressure Ventilation on Cardiac Performance
59 Citations1983James L. Robotham, Steven M. Scharf
It is clear that the physiologic events occurring during normal conditions are present but may be relatively less important under pathophysiologic conditions and only with a full understanding of both spontaneous respiration and conventional IPPV can the full implications of this new mode of ventilation be appreciated.
Archives of Disease in ChildhoodCor pulmonale as a result of chronic nasopharyngeal obstruction due to hypertrophied tonsils and adenoids.
54 Citations1969F J Macartney, J. Panday +1 more
The clinical, electrocardiographic, and radiological findings in 3 patients, together with the results of cardiac catheterization in 2 of them are presented.
Diseases of the ChestTonsillar Hypertrophy, Airway Obstruction, Alveolar Hypoventilation, and Cor Pulmonale in Twin Brothers
47 Citations1969Rashid A. Massumi, R.K. Sarin +5 more
Twin brothers suffering from severe alveolar hypoventilation secondary to tonsillar hypertrophy are presented, confirming a cause-effect relationship between upper airway obstruction and the cardiac complications.
CHEST JournalCor Pulmonale Secondary to Upper Airway Obstruction
35 Citations1975Daniel L. Levin, Alexander J. Muster +4 more
Diagnosis of this syndrome should be suspected when clinical and roentgenographic findings of biventricular heart failure are associated with right ventricular hypertrophy on electrocardiogram and the diagnosis of alveolar hypoventilation is confirmed.
HeartExercise radionuclide ventriculography in children: normal values for exercise variables and right and left ventricular function.
26 Citations1985Mark D. Parrish, Robert J. Boucek +4 more
It is concluded that exercise radionuclide ventriculography is an excellent technique for a combined assessment of exercise capacity and an evaluation of ventricular size and performance in children.
Intensive Care MedicinePulmonary edema secondary to chronic upper airway obstruction. Hemodynamic study in a child
18 Citations1984Shaul Sofer, R. W. Baer +3 more
The highly negative pleural pressure which existed during upper airway obstruction indicated an elevation of transmural left ventricular end diastolic pressure (compared to pulmonary wedge pressure) and thus, suggested that the pulmonary edema in this syndrome is secondary to both — right and left heart failure.
The Journal of PediatricsEchocardiographic changes in children with pulmonary hypertension secondary to upper airway obstruction
13 Citations1978Eliezer Nussbaum, Stephen S. Hirschfeld +3 more
When right ventricular ejection time and RV pre-ejection period are measured from the pulmonary valve echocardiogram, a RPEP/RVET ratio greater than 0.35 has been associated with increased pulmonary vascular resistance.