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Distribution and Determinants of Blood Pressure in Free-Living Children

Developments in cardiovascular medicinePublished 1 January 1980
Albert Hofman, H. A. Valkenburg
Citations11

TL;DR

The finding of early lesions in the aorta and coronary arteries of children and young adults has led to the statement that atherosclerosis is a pediatric problem essentially and epidemiological research of determinants of atherogenesis in childhood can be motivated by two main objectives.

Abstract

The growing popularity of the idea that the roots of atherosclerosis can be traced in young individuals has evoked many studies of cardiovascular risk indicators in childhood [1]. The finding of early lesions in the aorta and coronary arteries of children [2] and young adults [3] has led to the statement that atherosclerosis is a pediatric problem essentially [4]. Epidemiological research of determinants of atherogenesis in childhood can be motivated by two main objectives. Firstly, studies of the distribution and determinants of cardiovascular risk indicators can provide insight into the pathogenesis of atherosclerosis. Secondly, when atherosclerotic lesions are present in children, interventive measures implemented early in life can possibly prevent the development of atherosclerotic complications later.

Keywords

Medicine