Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels–Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles
Tetrahedron LettersPublished 13 September 2009
Marco Radi, Vincenzo Bernardo, Beatrice Bechi, Daniele Castagnolo, Mafalda Pagano, Maurizio Botta
Citations80
SJR quartileQ3
SJR score0.33
SNIP0.43
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Abstract
A rapid protocol for the multicomponent microwave-assisted organocatalytic domino Knoevenagel/hetero Diels–Alder reaction (DKHDA) has been developed for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. The reported procedure could be used for the fast generation of novel substituted 2,3-dihydropyran[2,3-c]pyrazoles with potential anti-tuberculosis activity.
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ChemistryMedicine
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