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A substance P projection to the hippocampus

Brain ResearchPublished 1 June 1981
Steven R. Vincent, Edith G. McGeer
Citations52
SJR quartileQ2
SJR score0.85
SNIP0.72

TL;DR

Electrolytic lesions of the septal area in the rat resulted in a major decrease in the activity of choline acetyltransferase in the hippocampus, consistent with the interruption of thesepto-hippocampal cholinergic pathway.

Abstract

Electrolytic lesions of the septal area in the rat resulted in a major decrease in the activity of choline acetyltransferase in the hippocampus, consistent with the interruption of the septo-hippocampal cholinergic pathway. These lesions also significantly decreased the levels of substance P in the hippocampus. It is suggested that a substance P projection to the hippocampus arises in or passes through the septal area.

Keywords

NeuroscienceBiochemistry, Genetics and Molecular Biology