Dietary factors and the risk of endometrial cancer
CancerPublished 1 June 1993
Fabio Levi, Carlo La Vecchia, Silvia Franceschi, Eva Negri
Citations177
SJR quartileQ1
SJR score2.95
SNIP1.90
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
This study focuses on the part of endometrial cancer that is associated with overweight, but little is known on its possible relationship with specific aspects of diet.
Abstract
The current study suggests that, aside from the predictable adverse effects of overeating and consequent overweight, some qualitative aspects of the habitual diet may also be associated with the risk of endometrial cancer, chiefly, the intake of animal proteins and fat (directly) and of fresh fruit, vegetables, and fibers (inversely).
Keywords
Medicine
JNCI Journal of the National Cancer InstituteStatistical Aspects of the Analysis of Data From Retrospective Studies of Disease
14,860 Citations1959Nathan Mantel, William Haenszel
Cancer Incidence in Five Continents
8,539 Citations1970Richard Doll, C. S. Muir +1 more
Statistical Methods in Cancer Research
6,727 Citations1980N. E. Breslow
American Journal of EpidemiologyRE: “TOTAL ENERGY INTAKE: IMPLICATIONS FOR EPIDEMIOLOGIC ANALYSES”
2,725 Citations1991Juni Palmgren, Lawrence H. Kushi
American Journal of EpidemiologyTOTAL ENERGY INTAKE: IMPLICATIONS FOR EPIDEMIOLOGIC ANALYSES
2,719 Citations1986Walter C. Willett, Meir J. Stampfer
While pitfalls in the manipulation and interpretation of energy intake data in epidemiologic studies have been emphasized, these considerations also highlight the usefulness of obtaining a measurement of total caloric intake, which is not accomplished with nutrient density measures of dietary intake.
McCance and Widdowson's The Composition of Foods
2,217 Citations2002Public Health England
The British tables of Paul and Southgate provide by far the most extensive introductory and explanatory material with the tables and is a resource which is often utilized.
JNCI Journal of the National Cancer InstituteAssociation of Cancer Sites With Tobacco and Alcohol Consumption and Socioeconomic Status of Patients: Interview Study From the Third National Cancer Survey
663 Citations1977Roger R. Williams, John W. Horm
Age, race, sex, smoking, drinking, education, income, parity, foreign birth, marital status, and geographic location were used as stratification variables separately or in combination when appropriate to assess and control for their potentially confounding affects and to examine results in different strata to assess interaction.
American Journal of EpidemiologyTHE EPIDEMIOLOGY OF SERUM SEX HORMONES IN POSTMENOPAUSAL WOMEN
487 Citations1989Jane A. Cauley, James P. Gutai +3 more
The data suggest interesting relations between environmental and lifestyle factors and serum sex hormones, which are potentially modifiable and, hence, if associations between sex hormones and disease exist, modification of these factors could affect disease risks.
Gynecologic OncologyThe epidemiology of endometrial cancer
406 Citations1991Fabio Parazzini, Carlo La Vecchia +2 more
Although endometrial cancer rates were found to be higher in richer countries and urban populations, there is now evidence of some changes in the socioeconomic determinants of the disease in developed countries.
American Journal of EpidemiologyINCREASED INCIDENCE OF CARCINOMA OF THE BREAST ASSOCIATED WITH ABDOMINAL ADIPOSITY IN POSTMENOPAUSAL WOMEN
335 Citations1990A. R. Folsom, Susan A. Kaye +4 more
The waist-to-hip circumference ratio was investigated in a nested case-control study of 41,837 postmenopausal Iowa women to find two plausible explanations for elevated breast cancer incidence in women with abdominal adiposity: 1) increased concentrations of non-protein-bound estrogens due to reduced sex hormone binding globulin, or 2) increased conversion of adrenal androgens to estrone with abdominal fat.
British Journal of CancerNutrient intakes in relation to cancer incidence in Hawaii
207 Citations1981Laurence N. Kolonel, Jean H. Hankin +4 more
A representative sample of 4657 adults greater than or equal to 45 years of age from the 5 main ethnic groups in Hawaii were interviewed during 1977-1979 regarding their diets, and significant positive associations were found for 6 of the cancer sites.
PubMedEndometrial cancer, obesity, and body fat distribution.
193 Citations1991Harland Austin, J.Max Austin +3 more
A strong, positive relationship between overall obesity and endometrial cancer was found and there was a statistically significant, independent positive effect of a high subscapular to tricep skinfold ratio, a measure of central versus peripheral obesity, on endometrian cancer risk.
JNCI Journal of the National Cancer InstituteDietary Fat Reduction and Plasma Estradiol Concentration in Healthy Postmenopausal Women
173 Citations1990R. L. Prentice, David M. Thompson +4 more
A review of case-control studies indicates that a 17% reduction in plasma estradiol may explain a noteworthy component of the international variation in breast cancer incidence.
JNCI Journal of the National Cancer InstituteA Case-Control Study of Dietary and Nondietary Factors in Ovarian Cancer<xref ref-type="fn" rid="FN2">2</xref>
172 Citations1983T. Byers, James R. Marshall +3 more
It is demonstrated that the apparent protective effect of vitamin A in the 30- to 49-year age group (but not dietary fiber) was independent of the nondietary factors analyzed in this study (P less than .05).
CancerNutrition and diet in the etiology of endometrial cancer
132 Citations1986Carlo La Vecchia, Adriano Decarli +2 more
D Dietary information collected in this study probably is too limited and inconsistent to permit analysis of biologic correlates of these findings or discussion of their potential implications in terms of prevention on a public health scale, but the mere existence of differences in reported diet between endometrial cancer cases and controls is of interest and may warrant further, more detailed investigation.
PubMedAssociation of change in body mass with breast cancer.
96 Citations1990Rachel Ballard‐Barbash, Arthur Schatzkin +2 more
It is suggested that gain inadult body mass is a predictor of breast cancer risk independent of adult body mass and avoidance of marked weight gain during adult life may reduce the risk of breastcancer.
Preventive MedicineDiet and the excretion and enterohepatic cycling of estrogens
92 Citations1987Sherwood L. Gorbach, Barry R. Goldin
It is indicated that diet can alter the route of excretion of estrogen by influencing the enterohepatic circulation and that this, in turn, influences plasma estrogen levels.
Tabelle di composizione degli alimenti
84 Citations1987F Fidanza, N. Versiglioni
International Journal of CancerEarly‐age body size, adult weight gain and endometrial cancer risk
70 Citations1991Loı̈c Le Marchand, Lynne R. Wilkens +1 more
It is suggested that obesity affects the late stages of endometrial carcinogenesis, and the possibility that one or more determinants of weight gain may be independently associated withendometrial cancer risk is considered.
JNCI Journal of the National Cancer InstituteEndometrial Cancer: Biochemical and Clinical Correlates
66 Citations1991Erlio Gurpide
In vivo and in vitro studies on normal and neoplastic tissues are providing evidence of paracrine influences on epithelial cell proliferation, and tamoxifen as adjuvant therapy for breast cancer has recently been found to increase the risk for development of endometrial cancer.
European Journal of Cancer and Clinical OncologyReproductive factors and cancers of the breast, ovary and endometrium
49 Citations1989Silvia Franceschi
The lesson from the recent studies on pregnancy-related events and breast cancer is, however, that initially a decrease of old certainties must be expected to derive from the accumulation of new, better epidemiological data.
International Journal of EpidemiologyAlcoholic Beverage Consumption and the Risk of Endometrial Cancer
48 Citations1989Linda A. Webster, Noel S. Weiss
It is argued that alcohol ingestion may reduce a woman's risk of endometrial cancer, particularly if she is overweight, and was virtually absent in lean women.
American Journal of EpidemiologyRE: “TOTAL ENERGY INTAKE: IMPLICATIONS FOR EPIDEMIOLOGIC ANALYSES”
39 Citations1989Malcolm C. Pike, Leslie Bernstein +1 more
Cancer Causes & ControlOral contraceptives and the risk of endometrial cancer
37 Citations1991Fabio Levi, Carlo La Vecchia +6 more
This study provides further evidence for the protective effect of OCs against risk of endometrial cancer, and requires continued evaluation to assess the long-term implications and public health impact of OC use.
Nutrition and CancerDiet and hormones in the epidemiology of breast and endometrial cancers
34 Citations1979Bruce K. Armstrong
European Journal of Cancer and Clinical OncologyNutritional factors and cancers of the breast, endometrium and ovary
29 Citations1989Carlo La Vecchia
The only clear indication for prevention is that a reduction of overweight would avoid a substantial number of cases of endometrial and post-menopausal breast cancer.