Tritiated Imipramine Binding Sites Are Decreased in the Frontal Cortex of Suicides
SciencePublished 18 June 1982
Michael Stanley, Joanne Virgilio, Samuel Gershon
Citations471
SJR quartileQ1
SJR score10.42
SNIP6.62
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TL;DR
Binding characteristics of tritiated imipramine were determined in the frontal cortex of suicides and well-matched controls and were consistent with reports of decreased tritiations in the platelets of patients diagnosed as having a major affective disorder.
Abstract
Binding characteristics of tritiated imipramine were determined in the frontal cortex of suicides and well-matched controls. Maximal binding was significantly lower in brains from the suicides. This finding is consistent with reports of decreased tritiated imipramine binding in the platelets of patients diagnosed as having a major affective disorder.
Keywords
MedicineNeuroscience
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