Meta-Analyses in Orthopaedic Surgery
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TL;DR
The majority of meta-analyses on orthopaedic-surgery-related topics have methodological limitations, and the ultimate quality of a meta-analysis depends on the quality of the primary studies on which it is based.
Abstract
The majority of meta-analyses on orthopaedic-surgery-related topics have methodological limitations. Limitation of bias and improvement in the validity of the meta-analyses can be achieved by adherence to strict scientific methodology. However, the ultimate quality of a meta-analysis depends on the quality of the primary studies on which it is based. A meta-analysis is most persuasive when data from high-quality randomized trials are pooled.
