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MRI-PET Registration with Automated Algorithm

Journal of Computer Assisted TomographyPublished 1 July 1993
Roger P. Woods, John C. Mazziotta, and Simon R. Cherry
Citations1,626
SJR quartileQ3
SJR score0.42
SNIP0.46

TL;DR

Modifications to this method that allow for cross-modality registration of MRI and PET brain images obtained from a single subject are described and validated quantitatively using data from patients with stereotaxic fiducial markers rigidly fixed in the skull.

Abstract

The method has been validated quantitatively using data from patients with stereotaxic fiducial markers rigidly fixed in the skull. Maximal three-dimensional errors of < 3 mm and mean three-dimensional errors of < 2 mm were measured. Computation time on a SPARCstation IPX varies from 3 to 9 min to align MR image sets with [18F]fluorodeoxyglucose PET images. The MR alignment with noisy H2(15)O PET images typically requires 20-30 min.

Keywords

Medicine