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Clinical severity of Alzheimer's disease is associated with PIB uptake in PET

Neurobiology of AgingPublished 19 March 2008
Timo Grimmer, Gjermund Henriksen, Hans‐Jürgen Wester, Hans Förstl, William E. Klunk, Chester A. Mathis
Citations92
SJR quartileQ1
SJR score1.45
SNIP0.92

TL;DR

The CDR-SOB score is significantly associated with [11C]PIB uptake in patients with AD, and is a potential surrogate marker of dementia severity.

Abstract

The CDR-SOB score is significantly associated with [11C]PIB uptake in patients with AD. Thus [11C]PIB is a potential surrogate marker of dementia severity.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology