Prevention of HIV Infection in Street-Recruited Injection Drug Users
JAIDS Journal of Acquired Immune Deficiency SyndromesPublished 1 September 2000
Edgar R. Monterroso, Merle E. Hamburger, David Vlahov, Don C. Des Jarlais, Lawrence J. Ouellet, Frederick L. Altice
Citations50
SJR quartileQ1
SJR score1.04
SNIP0.81
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
In this large multicity study of IDUs in the United States, several HIV prevention strategies appeared to be individually and partially effective; these results indicate the continued need for, and substantial gaps in, effective approaches to preventing HIV infection in drug users.
Abstract
In this large multicity study of IDUs in the United States, several HIV prevention strategies appeared to be individually and partially effective; these results indicate the continued need for, and substantial gaps in, effective approaches to preventing HIV infection in drug users.
Keywords
Medicine
Sociological Methods & ResearchSnowball Sampling: Problems and Techniques of Chain Referral Sampling
5,416 Citations1981Patrick Biernacki, Dan Waldorf
Social ProblemsTargeted Sampling: Options for the Study of Hidden Populations
1,472 Citations1989John K. Watters, Patrick Biernacki
Targeted sampling provides a cohesive set of research methods that can help researchers study health or social problems that exist among populations that are difficult to reach because of their attributed social stigma, legal status, and consequent lack of visibility.
New England Journal of MedicineIntersecting Epidemics -- Crack Cocaine Use and HIV Infection among Inner-City Young Adults
587 Citations1994Brian R. Edlin, Kathleen L. Irwin +8 more
In poor, inner-city communities young smokers of crack cocaine, particularly women who have sex in exchange for money or drugs, are at high risk for HIV infection.
American Journal of Public HealthThe estimated prevalence and incidence of HIV in 96 large US metropolitan areas.
555 Citations1996Scott D. Holmberg
Relatively high prevalences of HIV in at-risk heterosexual persons in several cities indicate the potential for an increase in transmission among them, and the size and direction of the human immunodeficiency virus epidemic in US metropolitan statistical areas with populations greater than 500,000 is estimated.
The LancetHIV incidence among injecting drug users in New York City syringe-exchange programmes
410 Citations1996Don C. Des Jarlais, Michael Marmor +6 more
An individual-level protective effect against HIV infection associated with participation in a syringe-exchange programme is observed and Sterile injection equipment should be legally provided to reduce the risk of HIV infection in persons who inject illicit drugs.
American Journal of EpidemiologyHigh Rates of HIV Infection among Injection Drug Users Participating in Needle Exchange Programs in Montreal: Results of a Cohort Study
308 Citations1997Julie Bruneau, F Lamothe +5 more
Risk elevations for HIV infection associated with NEP attendance were substantial and consistent in all three risk assessment scenarios in the authors' cohort of injection drug users, despite extensive adjustment for confounders.
JAMASyringe and Needle Exchange as HIV/AIDS Prevention for Injection Drug Users
285 Citations1994John K. Watters
The hypothesis that a syringe exchange program would stimulate increased drug abuse in terms of frequency of injection or recruitment of new and/or younger users was not supported.
American Journal of Public HealthReduced risk of hepatitis B and hepatitis C among injection drug users in the Tacoma syringe exchange program.
250 Citations1995Holly Hagan, Des Jarlais +3 more
The results suggest that use of the exchange led to a significant reduction in hepatitis B and hepatitis C in the county and may have also prevented a substantial proportion of human immunodeficiency virus infections in injection drug users.
Journal of Drug IssuesThe Alive Study: A Longitudinal Study of HIV-1 Infection in Intravenous Drug Users: Description of Methods
194 Citations1991David Vlahov, James C. Anthony +6 more
A cohort in Baltimore Maryland in 1988–1989 was established to identify risk factors for infection with the human immunodeficiency virus and for progression to the acquired immunODeficiency syndrome (AIDS) among intravenous drug users and methodological issues for enhancing recruitment and retention of drug users are discussed.
JAMAContinuity and change within an HIV epidemic. Injecting drug users in New York City, 1984 through 1992
147 Citations1994Don C. Des Jarlais
AIDSThe impact of the needle and syringe-exchange programme in Amsterdam on injecting risk behaviour
132 Citations1989C. Hartgers, Ernst C. Buning +3 more
It is argued that an exchange programme should be complemented with other prevention approaches, i.e. intensive counselling and the spread of leaflets with information on cleaning used needles with bleach, since young male injectors are more at risk of borrowing independent of exchanging.
American Journal of EpidemiologyNew Evidence on Intravenous Cocaine Use and the Risk of Infection with Human Immunodeficiency Virus Type 1
125 Citations1991James C. Anthony, David Vlahov +4 more
The results lend support to the abiding concern about the risk of HIV infection among cocaine users and allow a test for whether the association was a spurious artifact of studying drug users recruited solely from drug treatment programs.
American Journal of Public HealthDeclining seroprevalence in a very large HIV epidemic: injecting drug users in New York City, 1991 to 1996.
121 Citations1998Don C. Des Jarlais, Theresa E. Perlis +12 more
The reductions in HIV seroprevalence seen among injecting drug users in New York City from 1991 through 1996 indicate a new phase in this large HIV epidemic, potential explanatory factors include the loss of HIV-seropositive individuals through disability and death and lower rates of risk behavior leading to low HIV incidence.
AIDSNeedle exchange use among a cohort of injecting drug users
117 Citations1996Ellie E. Schoenbaum, Diana Hartel +1 more
Methadone‐treated IDU with access to a needle exchange reduced injecting and needle‐sharing, which began at least 4 years before the needle exchange opened, and should not be viewed as discordant with methadone treatment.
Journal of Acquired Immune Deficiency Syndromes & Human RetrovirologyRisk Behavior and HIV Infection Among New Drug Injectors in the Era of AIDS in New York City
100 Citations1999Don C. Des Jarlais, Samuel R. Friedman +6 more
AIDSChanges in HIV risk behaviour in clients of syringe-exchange schemes in England and Scotland
92 Citations1989Martin C. Donoghoe, Gerry V. Stimson +2 more
Overall, changes in HIV risk behaviour show small but encouraging trends and support arguments that injectors can be helped to change their behaviour, which could be of cumulative importance in reducing the spread of HIV.
AIDSHow effective are risk-reduction interventions targeting injecting drug users?
90 Citations1994Robert E. Booth, John K. Watters
The Journal of Infectious DiseasesDifferences in the Incidence of Hepatitis B and Human Immunodeficiency Virus Infections among Injecting Drug Users
55 Citations1996Orin S. Levine, David Vlahov +3 more
HBV seroconversion predicted subsequent HIV seroconversions among male IDUs but not among female IDUs, and probably has limited utility as a surrogate outcome measure for incident HIV.
EpidemiologyHIV SEROCONVERSION AND DISINFECTION OF INJECTION EQUIPMENT AMONG INTRAVENOUS DRUG USERS, BALTIMORE, MARYLAND
38 Citations1991David Vlahov, Alvaro Muntoz +5 more
A limited protective effect of disinfectant use in the field is suggested which may be more beneficial to those injecting in shooting galleries, and who used disinfectants some of the time.
